Department of Radiodiagnosis and Imaging, SKIMS Soura, Srinagar 190011, India.
Department of Anaesthesia, SKIMS Soura, Srinagar 190011, India.
Medicina (Kaunas). 2023 Feb 27;59(3):472. doi: 10.3390/medicina59030472.
: In December 2019, a flu-like illness began in the Chinese city of Wuhan. This sickness mainly affected the lungs, ranging from a minor respiratory tract infection to a severe lung involvement that mimicked the symptoms of Severe Acute Respiratory Syndrome (SARS). The World Health Organization (WHO) labelled this sickness as a pandemic in March 2020, after it quickly spread throughout the world population. It became clear, as the illness progressed, that people with concomitant illnesses, particularly diabetes mellitus (DM) and other immunocompromised states, were outmatched by this illness. This study was aimed to evaluate the correlation between Computed Tomographic Severity Score (CTSS) and underlying diabetes mellitus in coronavirus disease (COVID)-19 patients. : This was a hospital-based prospective study in which a total of 152 patients with reverse transcriptase polymerase chain reaction (RT-PCR) positive COVID status who underwent high-resolution computed tomography (HRCT) of the chest were evaluated and categorized into mild, moderate and severe cases based on the extent of lung parenchymal involvement. A total score from 0-25 was given, based on the magnitude of lung involvement. Statistical analysis was used to derive a correlation between DM and CTSS, if any. : From our study, it was proven that patients with underlying diabetic status had more severe involvement of the lung as compared to non-diabetics, and it was found to be statistically significant ( = 0.024). : On analysis of what we found based on the study, it can be concluded that patients with underlying diabetic status had a more prolonged and severe illness in comparison to non-diabetics, with higher CTSS in diabetics than in non-diabetics.
2019 年 12 月，一种类似流感的疾病在中国武汉市开始出现。这种疾病主要影响肺部，从轻微的呼吸道感染到严重的肺部受累，类似于严重急性呼吸综合征（SARS）的症状。世界卫生组织（WHO）在 2020 年 3 月将这种疾病标记为大流行，因为它迅速在全球人口中传播。随着疾病的发展，很明显，患有合并症的人，特别是糖尿病（DM）和其他免疫功能低下的状态，无法与这种疾病抗衡。这项研究旨在评估计算机断层扫描严重程度评分（CTSS）与冠状病毒疾病（COVID-19）患者潜在糖尿病之间的相关性。
这是一项基于医院的前瞻性研究，共评估了 152 名逆转录聚合酶链反应（RT-PCR）阳性 COVID 患者，这些患者接受了高分辨率胸部计算机断层扫描（HRCT），并根据肺实质受累的程度分为轻度、中度和重度。根据肺部受累的程度，给出了从 0 到 25 的总分。使用统计分析来得出 DM 和 CTSS 之间的相关性（如果有）。
从我们的研究中可以证明，与非糖尿病患者相比，患有潜在糖尿病状态的患者肺部受累更严重，这具有统计学意义（=0.024）。
根据我们基于该研究的发现进行分析，可以得出结论，与非糖尿病患者相比，患有潜在糖尿病状态的患者病情更长且更严重，糖尿病患者的 CTSS 高于非糖尿病患者。
