Glassman Ira, Nguyen Kevin H, Booth Michelle, Minasyan Marine, Cappadona Abby, Venketaraman Vishwanath
College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
WesternU Health Patient Care Center, Western University of Health Sciences, Pomona, CA 91766, USA.
Pathogens. 2023 Mar 3;12(3):408. doi: 10.3390/pathogens12030408.
Septic arthritis is a synovial fluid and joint tissue infection with significant morbidity and mortality risk if not diagnosed and treated promptly. The most common pathogen to cause septic arthritis is , a Gram-positive bacterium. Although diagnostic criteria are in place to guide the diagnosis of staphylococcal septic arthritis, there is a lack of adequate sensitivity and specificity. Some patients present with atypical findings which make it difficult to diagnose and treat in time. In this paper, we present the case of a patient with an atypical presentation of recalcitrant staphylococcal septic arthritis in a native hip complicated by uncontrolled diabetes mellitus and tobacco usage. We review current literature on diagnosing septic arthritis, novel diagnostic technique performance to guide future research and assist clinical suspicion, and current vaccine development for at-risk patients.
化脓性关节炎是一种滑膜液和关节组织感染,如果不及时诊断和治疗,会有很高的发病率和死亡率风险。引起化脓性关节炎最常见的病原体是一种革兰氏阳性菌。尽管有诊断标准来指导葡萄球菌性化脓性关节炎的诊断,但缺乏足够的敏感性和特异性。一些患者表现出非典型症状,这使得及时诊断和治疗变得困难。在本文中,我们介绍了一例患有顽固性葡萄球菌性化脓性关节炎的患者,该患者为天然髋关节,并发未控制的糖尿病和吸烟。我们回顾了目前关于诊断化脓性关节炎的文献、指导未来研究和辅助临床怀疑的新型诊断技术性能,以及针对高危患者的当前疫苗研发情况。