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[Paget’s disease of the nipple].

作者信息

Lützow-Holm Claus

出版信息

Tidsskr Nor Laegeforen. 2023 Mar 21;143(5). doi: 10.4045/tidsskr.22.0390. Print 2023 Mar 28.

DOI:10.4045/tidsskr.22.0390
PMID:36987906
Abstract

BACKGROUND

Paget's disease of the nipple comprises approximately 1 % of all breast cancers, and presents with unilateral eczematoid changes to the nipple, areola or surrounding skin. Symptoms can be pain, itching or stinging in the area.

CASE PRESENTATION

A female patient in her sixties presented to the skin clinic 18 months after initial detection of a rash surrounding her left nipple. Earlier ultrasound and mammography had not indicated pathology. Clinical suspicion and punch biopsies revealed a ductal carcinoma in situ. Surgical excision had to be repeated three times before the underlying malignancy was totally removed.

INTERPRETATION

Eczematoid changes in the nipple area are associated with underlying ductal carcinoma or a carcinoma in situ, and biopsies should be taken.

摘要

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