Xia Zhongyou, Fu Xueqin, Li Jinze, Yuan Xinzhu, Wu Ji, Tang Lingtong
Department of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College (University), Nanchong, Sichuan, China.
Department of Breast Surgery, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.
Aging Male. 2023 Dec;26(1):2166919. doi: 10.1080/13685538.2023.2166919.
This study aimed to summarize the current evidence regarding the feasibility of robot-assisted radical prostatectomy (RARP) in men aged over 75 years.
A comprehensive search of four electronic databases (China National Knowledge Infrastructure, PubMed, Web of Science, and Cochrane Library) was performed to identify eligible comparative studies as of April 2022. Parameters, including perioperative results and oncological and functional outcomes, were evaluated.
Seven articles with 7575 patients undergoing RARP were included in this study. Patients with prostate cancer were grouped by age ≥ 75 years versus < 75 years. Our results demonstrated that compared with the older group, the younger group had better potency ( < .00001). However, there were no significant differences in operation time ( = .29), estimated blood loss ( = .13), length of hospital stay ( = .48), complications ( = .22), continence ( = .21), positive surgical margin ( = .28), and biochemical recurrence ( = .74) between the groups.
Our study revealed that the perioperative, oncological, and functional outcomes in men aged over 75 years undergoing RARP were not significantly different from those of their younger counterparts. RARP is feasible in men aged over 75 years.
本研究旨在总结目前关于75岁以上男性机器人辅助根治性前列腺切除术（RARP）可行性的证据。
对四个电子数据库（中国知网、PubMed、科学网和考克兰图书馆）进行全面检索，以确定截至2022年4月符合条件的比较研究。对围手术期结果、肿瘤学和功能结果等参数进行评估。
本研究纳入了7篇包含7575例接受RARP患者的文章。前列腺癌患者按年龄≥75岁和<75岁分组。我们的结果表明，与老年组相比，年轻组的性功能恢复情况更好（P<0.00001）。然而，两组之间在手术时间（P=0.29）、估计失血量（P=0.13）、住院时间（P=0.48）、并发症（P=0.22）、控尿情况（P=0.21）、手术切缘阳性（P=0.28）和生化复发（P=0.74）方面没有显著差异。
我们的研究表明，75岁以上男性接受RARP的围手术期、肿瘤学和功能结果与年轻男性相比没有显著差异。RARP在75岁以上男性中是可行的。
