Tsukada Hirotaka, Nguyen Thuy-Tien N, Breeze John, Masouros Spyros D
Department of Bioengineering, Imperial College London, UK.
Department of Bioengineering, Imperial College London, UK; Royal Centre for Defence Medicine, Queen Elizabeth Hospital Birmingham, UK.
J Mech Behav Biomed Mater. 2023 May;141:105776. doi: 10.1016/j.jmbbm.2023.105776. Epub 2023 Mar 11.
Injury due to the penetration of fragments into parts of the body has been the major cause of morbidity and mortality after an explosion. Penetrating injuries into the heart present very high mortality, yet the risk associated with such injuries has not been quantified. Quantifying this risk is key in the design of personal protection and the design of infrastructure. This study is the first quantitative assessment of cardiac penetrating injuries from energised fragments. Typical fragments (5-mm sphere, 0.78-g right-circular cylinder and 1.1-g chisel-nosed cylinder) were accelerated to a range of target striking velocities using a bespoke gas-gun system and impacted ventricular and atrial walls of lamb hearts. The severity of injury was shown to not depend on location (ventricular or atrial wall). The striking velocity with 50% probability of critical injury (Abbreviated Injury Scale (AIS) 5 score) ranged between 31 and 36 m/s across all 3 fragments used. These findings can help directly in reducing morbidity and mortality from explosive events as they can be implemented readily into models that aim to predict casualties in an explosive event, inform protocols for first responders, and improve design of infrastructure and personal protective equipment.
爆炸后,碎片穿透身体各部位造成的损伤一直是发病和死亡的主要原因。心脏穿透伤的死亡率极高,但此类损伤的风险尚未量化。量化这一风险是个人防护设计和基础设施设计的关键。本研究首次对带电碎片导致的心脏穿透伤进行了定量评估。使用定制气枪系统将典型碎片(5毫米球体、0.78克右旋圆柱体和1.1克凿形圆柱体)加速至一系列目标撞击速度,并撞击羊心脏的心室壁和心房壁。结果表明,损伤的严重程度并不取决于位置(心室壁或心房壁)。在所使用的所有3种碎片中,造成严重损伤(简明损伤定级标准(AIS)5级评分)概率为50%时的撞击速度在31至36米/秒之间。这些研究结果可直接有助于降低爆炸事件导致的发病率和死亡率,因为它们可轻易应用于旨在预测爆炸事件伤亡情况的模型,为急救人员的方案提供参考,并改进基础设施和个人防护装备的设计。