Jia Fang, Zhang Jingyu, Hu Yongcheng, Li Ping
Department of Anesthesia, Tianjin Hospital, Tianjin, People's Republic of China.
Department of Bone Oncology, Tianjin Hospital, Tianjin, People's Republic of China.
Int J Gen Med. 2023 Mar 22;16:1061-1068. doi: 10.2147/IJGM.S399961. eCollection 2023.
This study aimed to evaluate the pulmonary function of patients with solitary spinal metastases with the intention of providing a data-driven basis to evaluate cardiopulmonary function in patients with spinal metastases in the future.
This was a retrospective analysis of 157 patients with solitary spinal metastases in our hospital from January 2010 to December 2018. This study analyzed the influence of different stages of solitary spinal involvement on respiratory function, based on the spinal segment invaded by the metastases.
The highest proportion of solitary spinal metastases occurred at the thoracic level (49.7%), with the lowest proportion at the sacral level (3.9%). The largest number of patients were in the 60-69-year age group (34.6%). There was no significant difference in pulmonary function among patients with spinal metastases at different segments (all P > 0.05). The highest vital capacity (VC), forced expiratory volume in one second (FEV), and forced vital capacity (FVC) were observed in patients who were overweight (all P < 0.05). There were no significant relationships between pulmonary respiratory function and body mass index (BMI) groups in male patient with spinal metastases. In female patients, the highest VC, FEV, FVC, and maximum voluntary ventilation were observed in patients who were overweight (all P < 0.05).
Thoracic vertebral metastasis was the main type of solitary spinal metastatic tumor. Spinal metastases were more common at ages 60-69 years. There was no significant difference in pulmonary function among patients with spinal metastasis at different segments. Lung function was better in patients with spinal metastases who were overweight, especially in female patients.
本研究旨在评估孤立性脊柱转移瘤患者的肺功能，以便为未来评估脊柱转移瘤患者的心肺功能提供数据驱动的依据。
这是一项对2010年1月至2018年12月我院157例孤立性脊柱转移瘤患者的回顾性分析。本研究根据转移瘤侵犯的脊柱节段，分析孤立性脊柱受累的不同阶段对呼吸功能的影响。
孤立性脊柱转移瘤发生率最高的部位是胸椎（49.7%），最低的是骶椎（3.9%）。患者人数最多的年龄组为60 - 69岁（34.6%）。不同节段脊柱转移瘤患者的肺功能无显著差异（所有P>0.05）。超重患者的肺活量（VC）、一秒用力呼气容积（FEV）和用力肺活量（FVC）最高（所有P<0.05）。男性脊柱转移瘤患者的肺呼吸功能与体重指数（BMI）组之间无显著关系。在女性患者中，超重患者的VC、FEV、FVC和最大自主通气量最高（所有P<0.05）。
胸椎转移是孤立性脊柱转移瘤的主要类型。脊柱转移瘤在60 - 69岁更为常见。不同节段脊柱转移瘤患者的肺功能无显著差异。超重的脊柱转移瘤患者肺功能较好，尤其是女性患者。
