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Triple combination therapy for pancreatic cancer remodels stroma and improves survival.

作者信息

Vázquez-Arreguín Karina, Kaur Balveen

机构信息

Department of Pathology and Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA, USA.

出版信息

Mol Ther Oncolytics. 2023 Mar 21;29:15-16. doi: 10.1016/j.omto.2023.03.001. eCollection 2023 Jun 15.

DOI:10.1016/j.omto.2023.03.001
PMID:36992913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10041460/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76cd/10041460/c7c702b3312d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76cd/10041460/c7c702b3312d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76cd/10041460/c7c702b3312d/gr1.jpg

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本文引用的文献

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Mol Ther Oncolytics. 2022 Dec 7;28:31-43. doi: 10.1016/j.omto.2022.12.001. eCollection 2023 Mar 16.
2
Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: A Phase I Dose Escalation and Expansion Study.德法替尼、帕博利珠单抗和吉西他滨治疗晚期治疗难治性胰腺癌患者的 I 期剂量递增和扩展研究。
Clin Cancer Res. 2022 Dec 15;28(24):5254-5262. doi: 10.1158/1078-0432.CCR-22-0308.
3
Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.
瘤内溶瘤单纯疱疹病毒 G47∆ 治疗残留或复发性脑胶质瘤:一项 2 期试验
Nat Med. 2022 Aug;28(8):1630-1639. doi: 10.1038/s41591-022-01897-x. Epub 2022 Jul 21.
4
The complex relationship between integrins and oncolytic herpes Simplex Virus 1 in high-grade glioma therapeutics.整合素与溶瘤单纯疱疹病毒1在高级别胶质瘤治疗中的复杂关系。
Mol Ther Oncolytics. 2022 Jun 6;26:63-75. doi: 10.1016/j.omto.2022.05.013. eCollection 2022 Sep 15.
5
The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review.核焦点黏着激酶(FAK)在癌症中的作用:聚焦综述。
J Exp Clin Cancer Res. 2019 Jun 11;38(1):250. doi: 10.1186/s13046-019-1265-1.
6
Enhancing Therapeutic Efficacy of Oncolytic Herpes Simplex Virus-1 with Integrin β1 Blocking Antibody OS2966.用整合素 β1 阻断抗体 OS2966 增强溶瘤单纯疱疹病毒-1 的治疗效果。
Mol Cancer Ther. 2019 Jun;18(6):1127-1136. doi: 10.1158/1535-7163.MCT-18-0953. Epub 2019 Mar 29.
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Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.靶向粘着斑激酶可使胰腺癌对检查点免疫疗法产生反应。
Nat Med. 2016 Aug;22(8):851-60. doi: 10.1038/nm.4123. Epub 2016 Jul 4.
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