Regmi Binit U, Pathak Bishnu D, Subedi Ram C, Dhakal Bishal, Sapkota Suhail, Joshi Sushil, Poudel Ujjawal, Poudel Raju
Department of Neurology, Jibjibe Primary Health Care Center, Rasuwa, Nepal.
Department of Neurology, Grande International Hospital, Kathmandu, Nepal.
Oxf Med Case Reports. 2023 Mar 25;2023(3):omad016. doi: 10.1093/omcr/omad016. eCollection 2023 Mar.
We present a case of a 29-year-old immunocompetent female without any known comorbidities with intermittent headache and vomiting who was ultimately diagnosed with cryptococcal meningitis (CM). Though her neuroimaging findings were atypical to those commonly found in CM, she was diagnosed with CM with a cryptococcal antigen test. However, in contrast to the good prognosis as stated in the literature, she died during her course stay at the hospital. Therefore, cryptococcosis should be taken as differentials, even in an immunocompetent individual presenting with features suggestive of meningitis, to prevent the worst clinical outcome.
我们报告一例29岁免疫功能正常的女性病例，她没有任何已知的合并症，有间歇性头痛和呕吐症状，最终被诊断为隐球菌性脑膜炎（CM）。尽管她的神经影像学表现与CM中常见的表现不同，但通过隐球菌抗原检测，她被诊断为CM。然而，与文献中所述的良好预后相反，她在住院期间死亡。因此，即使是表现出脑膜炎特征的免疫功能正常个体，也应将隐球菌病列为鉴别诊断，以防止出现最坏的临床结果。
