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免疫功能正常患者发生的隐球菌性脑膜炎伴复发性小脑炎。

Cryptococcal meningitis with accompanying recurrent cerebellitis in an immunocompetent patient.

作者信息

Kaya Selçuk, Köksal Iftihar, Tosun Ilknur, Sarı Ahmet, Alioğlu Zekeriya

机构信息

Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon 61080, Turkey.

Department of Medical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon 61080, Turkey.

出版信息

Med Mycol Case Rep. 2012 Nov 6;1(1):127-9. doi: 10.1016/j.mmcr.2012.10.006. eCollection 2012.

DOI:10.1016/j.mmcr.2012.10.006
PMID:24371758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3854632/
Abstract

This report describes a 46-year-old individual with normal immune status and a clinical course marked by headache and nausea-vomiting. He was diagnosed as having cryptococcal meningitis (CM) accompanying with cerebellitis. The interesting element was the observation of recurrent cerebellitis, never before reported in the literature for CM. He was successfully treated with antifungal and steroid therapy and discharged on day 330.

摘要

本报告描述了一名46岁免疫状态正常的个体，其临床病程以头痛和恶心呕吐为特征。他被诊断为患有伴有小脑炎的新型隐球菌性脑膜炎（CM）。有趣的是观察到复发性小脑炎，这在CM的文献中从未有过报道。他通过抗真菌和类固醇治疗成功治愈，并于第330天出院。

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本文引用的文献

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Universal screening of Tanzanian HIV-infected adult inpatients with the serum cryptococcal antigen to improve diagnosis and reduce mortality: an operational study.坦桑尼亚 HIV 感染成年住院患者血清隐球菌抗原的普遍筛查以改善诊断和降低死亡率：一项操作性研究。
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Comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection.比较 HIV 感染者和非 HIV 感染者隐球菌性脑膜炎的临床特征和死亡率。
J Microbiol Immunol Infect. 2011 Oct;44(5):338-45. doi: 10.1016/j.jmii.2010.08.011. Epub 2011 Jan 20.
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MRI findings of cerebral cryptococcosis in immunocompetent patients.免疫功能正常患者脑隐球菌病的MRI表现
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