Tandon R K, Sarin S K, Bose S L, Berry M, Tandon B N
Gastroenterol Jpn. 1986 Feb;21(1):17-22. doi: 10.1007/BF02775935.
Intestinal tuberculosis is still common in developing countries. In 186 patients with intestinal tuberculosis, clinical features, radiological findings and complications were carefully recorded and compared with those from earlier studies with a view to study any possible changes after the liberal use of antitubercular drugs. Sixty two percent of the patients in the present series had had prior exposure to antitubercular drugs. The incidence of systemic symptoms like fever and anorexia, alternating diarrhoea and constipation, peritoneal and lymph node involvements and associated pulmonary lesions were less frequently observed. On the other hand, an indolent and complicated course with intestinal obstruction (47%) and lower gastrointestinal bleeding (5.5%) and frequent colonic involvement (19%) often necessitating surgical intervention appeared to have become more frequent than reported in earlier series. Awareness of these changes in the clinical profile of intestinal tuberculosis should be helpful in the diagnosis and management of the condition.
肠结核在发展中国家仍然很常见。对186例肠结核患者的临床特征、影像学表现及并发症进行了详细记录,并与早期研究结果进行比较,以研究在广泛使用抗结核药物后是否有任何可能的变化。本系列中62%的患者曾接触过抗结核药物。发热、厌食等全身症状、腹泻与便秘交替、腹膜及淋巴结受累以及相关肺部病变的发生率较以往研究中观察到的更低。另一方面,病程进展缓慢且复杂,伴有肠梗阻(47%)、下消化道出血(5.5%)以及结肠频繁受累(19%),常需手术干预,这种情况似乎比早期系列报道更为常见。认识到肠结核临床特征的这些变化,有助于对该病进行诊断和管理。