Takehana Kazuya
Division of Cardiology, Department of Medicine II, Kansai Medical University, Osaka, Japan.
Ann Nucl Cardiol. 2021;7(1):63-66. doi: 10.17996/anc.21-00147. Epub 2021 Aug 31.
In recent years, the requirement for pharmacological stress myocardial perfusion imaging (SPECT) has increased, and adenosine stress testing is now the mainstream. Selective adenosine A2A receptor agonists will be applied clinically in the future. By selectively activating only A2A receptors, it can reduce complications such as bronchospasm, hypotension, and bradycardia, which have been problems with adenosine stress tests. In addition, since this drug can be administered in bolus injection, it has the advantage of being able to perform the test at one root.
近年来，药理应激心肌灌注显像（SPECT）的需求有所增加，腺苷负荷试验目前是主流。选择性腺苷A2A受体激动剂未来将应用于临床。通过仅选择性激活A2A受体，它可以减少诸如支气管痉挛、低血压和心动过缓等并发症，这些一直是腺苷负荷试验存在的问题。此外，由于这种药物可以静脉推注给药，它具有能够一次完成检查的优势。
