Li Yin
CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Sheng Wu Gong Cheng Xue Bao. 2023 Mar 25;39(3):807-841. doi: 10.13345/j.cjb.230097.
This article summarizes the reviews and original research papers published in Chinese Journaol of Biotechnology in the area of biomanufacturing driven by engineered organisms in the year of 2022. The enabling technologies including DNA sequencing, DNA synthesis, and DNA editing as well as regulation of gene expression and cell modeling were highlighted. This was followed by discussing the biomanufacturing of biocatalytics products, amino acids and its derivatives, organic acids, natural products, antibiotics and active peptides, functional polysaccharides, and functional proteins. Lastly, the technologies for utilizing C1 compounds and biomass as well as synthetic microbial consortia were discussed. The aim of this article was to help the readers to gain insights into this rapidly developing field from the journal point of view.
本文总结了2022年发表于《中国生物工程杂志》上有关工程生物体驱动的生物制造领域的综述和原创研究论文。重点介绍了包括DNA测序、DNA合成、DNA编辑以及基因表达调控和细胞建模在内的使能技术。随后讨论了生物催化产品、氨基酸及其衍生物、有机酸、天然产物、抗生素和活性肽、功能性多糖以及功能性蛋白质的生物制造。最后，探讨了利用C1化合物和生物质的技术以及合成微生物群落。本文旨在帮助读者从期刊的角度深入了解这个快速发展的领域。
