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西澳大利亚州一家地区中心的儿科阴性阑尾切除率:一项为期五年的队列研究。

Paediatric negative appendicectomy rates at a regional Western Australian Centre: a five-year cohort study.

作者信息

Behrendorff Natasha, Palan Ranesh, McKitterick Tommy, Cover Jacinta

机构信息

General Surgery Department, South West Health Campus, Western Australia Country Health Service, Bunbury, Western Australia, Australia.

出版信息

ANZ J Surg. 2023 Jul-Aug;93(7-8):1987-1992. doi: 10.1111/ans.18446. Epub 2023 Mar 30.

Abstract

BACKGROUND

In acute appendicitis, decision-making around operative intervention for paediatric patients differs from adults due to a higher weight placed on clinical assessment and reduced rates of cross-sectional imaging. In regional settings, non-paediatric emergency doctors, general surgeons, and radiologists usually assess and manage this patient group. Differences have been observed in paediatric negative appendicectomy rates between general and paediatric centres.

METHODS

A retrospective cohort study was performed, identifying paediatric patients undergoing emergency appendicectomy at the Southwest Health Campus (Bunbury, Western Australia) from 2017 to 2021. The primary outcome measure was histopathology confirming the absence of transmural inflammation of the appendix. In addition, clinical, biochemical and radiological data were collected to identify predictors of negative appendicectomy (NA). Secondary outcome measures were hospital length-of-stay and post-operative complication rates.

RESULTS

Four hundred and twenty-one patients were identified, of which 44.9% had a negative appendicectomy. Statistically significant associations between female gender, white cell count less than 10 × 10 , neutrophil ratio less than 75%, low CRP and NA were observed. NA was not associated with a lower risk of re-admission or complications compared with appendicectomy for appendicitis.

CONCLUSIONS

Our centre's NA rate is higher than that observed in the literature at both non-paediatric and paediatric surgical centres. NA has similar morbidity risk to appendicectomy for uncomplicated appendicitis and offers a timely reminder that diagnostic laparoscopy in children is not benign.

摘要

背景

在急性阑尾炎中,由于更重视临床评估且横断面成像率降低,儿科患者手术干预的决策与成人不同。在地区环境中,非儿科急诊医生、普通外科医生和放射科医生通常对这一患者群体进行评估和管理。普通中心和儿科中心的儿科阴性阑尾切除率存在差异。

方法

进行了一项回顾性队列研究,确定了2017年至2021年在西南健康校区(西澳大利亚州本伯里)接受急诊阑尾切除术的儿科患者。主要结局指标是组织病理学证实阑尾无透壁性炎症。此外,收集了临床、生化和放射学数据,以确定阴性阑尾切除术(NA)的预测因素。次要结局指标是住院时间和术后并发症发生率。

结果

共确定421例患者,其中44.9%进行了阴性阑尾切除术。观察到女性、白细胞计数低于10×10、中性粒细胞比例低于75%、低CRP与NA之间存在统计学显著关联。与阑尾炎阑尾切除术相比,NA与再入院或并发症风险较低无关。

结论

我们中心的NA率高于非儿科和儿科外科中心文献中观察到的率。NA与单纯性阑尾炎阑尾切除术的发病风险相似,并及时提醒人们儿童诊断性腹腔镜检查并非无害。

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