Addenbrooke's Hospital, Cambridge, India.
Br J Surg. 2014 May;101(6):707-14. doi: 10.1002/bjs.9455. Epub 2014 Apr 2.
Appendicectomy for acute appendicitis in children may be performed in specialist centres by paediatric surgeons or in general surgery units. Service provision and outcome of appendicectomy in children may differ between such units.
This multicentre observational study included all children (aged less than 16 years) who had an appendicectomy at either a paediatric surgery unit or general surgery unit. The primary outcome was normal appendicectomy rate (NAR). Secondary outcomes included 30-day adverse events, use of ultrasound imaging and laparoscopy, and consultant involvement in procedures.
Appendicectomies performed in 19 paediatric surgery units (242 children) and 54 general surgery units (461 children) were included. Children treated in paediatric surgery units were younger and more likely to have a preoperative ultrasound examination, a laparoscopic procedure, a consultant present at the procedure, and histologically advanced appendicitis than children treated in general surgery units. The unadjusted NAR was significantly lower in paediatric surgery units (odds ratio (OR) 0.37, 95 per cent confidence interval 0.23 to 0.59; P < 0.001), and the difference persisted after adjusting for age, sex and use of preoperative ultrasound imaging (OR 0.34, 0.21 to 0.57; P < 0.001). Female sex and preoperative ultrasonography, but not age, were significantly associated with normal appendicectomy in general surgery units but not in paediatric surgery units in this adjusted model. The unadjusted 30-day adverse event rate was higher in paediatric surgery units than in general surgery units (OR 1.90, 1.18 to 3.06; P = 0.011). When adjusted for case mix and consultant presence at surgery, no statistically significant relationship between centre type and 30-day adverse event rate existed (OR 1.59, 0.93 to 2.73; P = 0.091).
The NAR in general surgery units was over twice that in paediatric surgery units. Despite a more severe case mix, paediatric surgery units had a similar 30-day adverse event rate to general surgery units. Service provision differs between paediatric and general surgery units.
小儿阑尾炎的阑尾切除术可由小儿外科医生在专科中心进行,也可在普通外科病房进行。小儿外科病房和普通外科病房的阑尾切除术服务提供和结果可能有所不同。
本多中心观察性研究纳入了所有在小儿外科病房或普通外科病房接受阑尾切除术的儿童(年龄小于 16 岁)。主要结局为正常阑尾切除术率(NAR)。次要结局包括 30 天不良事件、超声成像和腹腔镜检查的应用,以及顾问在手术中的参与情况。
纳入了 19 个小儿外科病房(242 例儿童)和 54 个普通外科病房(461 例儿童)的阑尾切除术。与普通外科病房相比,在小儿外科病房接受治疗的儿童年龄更小,更有可能在术前进行超声检查、腹腔镜手术、顾问在场且阑尾组织学表现更严重。未调整的 NAR 在小儿外科病房显著降低(比值比(OR)0.37,95%置信区间 0.23 至 0.59;P<0.001),且在调整年龄、性别和术前超声检查的使用后仍保持一致(OR 0.34,0.21 至 0.57;P<0.001)。在普通外科病房中,女性和术前超声检查与正常阑尾切除术显著相关,但在小儿外科病房中则不相关。未调整的 30 天不良事件发生率在小儿外科病房高于普通外科病房(OR 1.90,1.18 至 3.06;P=0.011)。在调整病例组合和手术时顾问的存在后,中心类型与 30 天不良事件发生率之间没有统计学显著关系(OR 1.59,0.93 至 2.73;P=0.091)。
普通外科病房的 NAR 是小儿外科病房的两倍多。尽管病例组合更为严重,但小儿外科病房的 30 天不良事件发生率与普通外科病房相似。小儿外科病房和普通外科病房的服务提供存在差异。