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与 ICU 中拔管失败相关的因素:一项病例对照研究。

Factors associated with extubation failure in an intensive care unit: a case-control study.

机构信息

Fundação Faculdade de Medicina de São José do Rio Preto, UTI 5 Bloco A, São José do Rio Preto, SP, Brazil.

Faculdade de Medicina de São José do Rio Preto, Departamento de Enfermagem Especializada, São José do Rio Preto, SP, Brazil.

出版信息

Rev Lat Am Enfermagem. 2023;31:e3864. doi: 10.1590/1518-8345.6224.3864.

DOI:10.1590/1518-8345.6224.3864
PMID:36995853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10077863/
Abstract

OBJECTIVE

to investigate the factors associated with extubation failure of patients in the intensive care unit.

METHOD

unpaired, longitudinal, retrospective and quantitative case-control with the participation of 480 patients through clinical parameters for ventilator weaning. Data were analyzed by: Fisher's exact test or the chi-square test; unpaired two-tailed Student's t test; and Mann-Whitney test. Significant P values lower than or equal to 0.05 were admitted.

RESULTS

of the patients, 415 (86.5%) were successful and 65 (13.5%) failed. Success group: the most negative fluid balance, APACHE II in 20 (14-25), weak cough in 58 (13.9%). Failure group: the most positive fluid balance, APACHE II in 23 (19-29), weak cough in 31 (47.7%), abundant amount of pulmonary secretions in 47.7%.

CONCLUSION

positive fluid balance and the presence of inefficient cough or inability to clear the airway were predictors of extubation failure.

摘要

目的

探讨与 ICU 患者拔管失败相关的因素。

方法

采用非配对、纵向、回顾性和定量病例对照研究,通过临床参数对 480 例患者进行呼吸机撤机。采用 Fisher 确切检验或卡方检验、未配对双尾 Student t 检验和 Mann-Whitney 检验进行数据分析。P 值小于或等于 0.05 为有统计学意义。

结果

患者中 415 例(86.5%)成功,65 例(13.5%)失败。成功组:液体负平衡最多,APACHE II 为 20(14-25),咳嗽无力 58 例(13.9%)。失败组:液体正平衡最多,APACHE II 为 23(19-29),咳嗽无力 31 例(47.7%),肺部分泌物多 47.7%。

结论

液体正平衡和低效咳嗽或不能清除气道的存在是拔管失败的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7997/10077863/b59aa05f3b49/1518-8345-rlae-31-e3864-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7997/10077863/b59aa05f3b49/1518-8345-rlae-31-e3864-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7997/10077863/b59aa05f3b49/1518-8345-rlae-31-e3864-gf1.jpg

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Predictive power of extubation failure diagnosed by cough strength: a systematic review and meta-analysis.咳嗽力量诊断拔管失败的预测能力:系统评价和荟萃分析。
Crit Care. 2021 Oct 12;25(1):357. doi: 10.1186/s13054-021-03781-5.
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[Weaning from invasive mechanical ventilation].有创机械通气的撤机
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Crit Care. 2024 Nov 12;28(1):366. doi: 10.1186/s13054-024-05135-3.
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Independent Risk Factors of Failed Extubation among Adult Critically Ill Patients: A Prospective Observational Study from Saudi Arabia.成年危重症患者拔管失败的独立危险因素:一项来自沙特阿拉伯的前瞻性观察研究。
Saudi J Med Med Sci. 2024 Jul-Sep;12(3):216-222. doi: 10.4103/sjmms.sjmms_19_24. Epub 2024 Jun 20.
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