[北海道地区通过大规模筛查发现的女性乳腺癌的统计学评估]

[The statistical evaluation of the female breast cancer detected by mass screening in Hokkaido].

作者信息

Imamura H, Tamura K, Uchino J, Sano H, Nakanishi M, Kakita A, Hata Y, Nishida O, Tsuburaya T, Konno T

出版信息

Hokkaido Igaku Zasshi. 1986 Jan;61(1):35-45.

Abstract

In Hokkaido, 113, 612 women were subjected to mass screening of breast cancer from 1973 to 1983. Out of them, 74, 285 (56.3%) were examined once and the remainder twice or more: 4,798 (4.2%) were advised to receive further precise examinations and 99.8% of them underwent the second examination. Breast cancer was detected in 377, in which 291 (77.2%) were detected by the first examination and 33 (3.8%) were so-called "interval cancer" with the mean interval of 19.3 months. The detection rate was 0.3%. Histologically non-invasive cancer was seen in 26 (6.9% of 377). Despite a recent significant increase in detection rate of the earlier stage of breast cancer, the present study showed no evidence of a decrease in advanced cancer. The prognosis of the patients who had curable operation revealed 86.9% in 5 year survival rate and 40% in 10 year survival rate.

摘要

1973年至1983年期间，北海道有113,612名女性接受了乳腺癌大规模筛查。其中，74,285名（56.3%）接受了一次检查，其余的接受了两次或更多次检查：4,798名（4.2%）被建议接受进一步的精确检查，其中99.8%的人接受了第二次检查。共检测出377例乳腺癌，其中291例（77.2%）通过首次检查被发现，33例（3.8%）为所谓的“间期癌”，平均间期为19.3个月。检出率为0.3%。组织学上的非浸润性癌有26例（占377例的6.9%）。尽管近年来早期乳腺癌的检出率显著提高，但本研究未显示晚期癌有减少的迹象。接受可治愈手术的患者的预后显示，5年生存率为86.9%，10年生存率为40%。