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[感染性心内膜炎抗生素给药前的手术结果]

[Surgical Outcomes Prior to Antibiotics Administration for Infective Endocarditis].

作者信息

Murakami Masahiko, Narukawa Takahiro, Yamaguchi Daisuke, Inoue Ryosai, Hirano Kouji, Maze Yasumi, Tokui Toshiya

机构信息

Department of Thoracic and Cardiovascular Surgery, Ise Red Cross Hospital, Ise, Japan.

出版信息

Kyobu Geka. 2023 Apr;76(4):265-269.

PMID:36997173
Abstract

OBJECT

We examined the surgical outcomes for infective endocarditis (IE) at our institution.

METHODS

Between January 2012 and March 2022, we operated on 43 patients who diagnosed active IE. We decided to perform surgery after antibiotics administration for at least two weeks.

RESULTS

The mean age was 63.9 years old, and 28 male were included. The affected valves were 12 aortic valves, and 26 mitral valved and five multi valves, the causative microorganisms were Staphylococcus aureus 14 patient, Staphylococcus spp. 3 patients, Streptococcus spp. 17 patients, Enterococcus spp. 3 patients, and others 6 patients. One patient underwent aortic valve repair, and 17 patients underwent aortic valve preplacement. Twenty four underwent mitral valve repair, and eight underwent mitral valve replacement. The duration of preoperative antibiotics administration was 27.7±2.1 days (median 28 days). There were six in-hospital death (motality 14.0%). The five-years survival rate was 78.1% and the freedom from cardiac events at five years was 88.4%.

CONCLUSION

The strategy for preoperative management and timing of surgery for IE patients at our institution was appropriate.

摘要

目的

我们研究了我院感染性心内膜炎(IE)的手术治疗结果。

方法

2012年1月至2022年3月期间,我们对43例诊断为活动性IE的患者进行了手术。我们决定在给予抗生素至少两周后进行手术。

结果

平均年龄为63.9岁,包括28名男性。受累瓣膜为12个主动脉瓣、26个二尖瓣和5个多瓣膜,致病微生物为金黄色葡萄球菌14例、葡萄球菌属3例、链球菌属17例、肠球菌属3例,其他6例。1例患者接受主动脉瓣修复,17例患者接受主动脉瓣置换。24例接受二尖瓣修复,8例接受二尖瓣置换。术前抗生素使用时间为27.7±2.1天(中位数28天)。有6例住院死亡(死亡率14.0%)。五年生存率为78.1%,五年无心脏事件生存率为88.4%。

结论

我院IE患者的术前管理策略和手术时机是合适的。

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