Department of Psychiatry, University of Oxford, Oxford, UK.
Department of Paediatric Neuropsychology, University Hospitals Bristol and Weston NHS Trust, Bristol, UK.
Syst Rev. 2023 Mar 30;12(1):58. doi: 10.1186/s13643-023-02187-4.
Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterised by progressive visuospatial and visuoperceptual impairment. Recent research shows that memory impairment can also occur as an early symptom of the condition and that the impairment can be ameliorated by providing support in the memory recall phase, for example, by presenting a related cue. In Alzheimer's disease (AD), which is defined by an amnestic syndrome, memory aids and strategies have been used to help support everyday memory, which in turn can have a positive impact on patient and carer outcomes. Similar support for PCA could be achieved by using memory aids and strategies which help to encode and/or retrieve information, yet there are currently no guidelines for memory strategies that may be suitable in PCA. Due to the central visual disorder that defines PCA, careful consideration is needed when making recommendations.
A scoping review will be conducted of published studies that have assessed memory aids and strategies in people with AD and related dementias where memory is considered a core or supplementary feature, with the aim of distinguishing those that may be suitable or adaptable for PCA. The systematic search will include the electronic databases MEDLINE, PsycINFO and CINAHL, using search terms for dementia and memory aids and strategies identified in pilot searches. Findings will be mapped and described based on methods used, population, clinical data and memory aids and strategies identified.
The scoping review will give an overview of the memory aids and strategies used in people with AD and related dementias and identify characteristics, modality and pragmatics to evaluate their suitability and adaptability for a PCA population. Tailored memory support strategies for people living with PCA could improve memory performance, with knock-on positive effects on patient and carer outcomes.
后部皮质萎缩（PCA）是一种神经退行性综合征，其特征是进行性视空间和视知觉障碍。最近的研究表明，记忆障碍也可能作为该疾病的早期症状出现，并且可以通过在记忆回忆阶段提供支持来改善这种障碍，例如通过呈现相关线索。在以遗忘综合征为特征的阿尔茨海默病（AD）中，已经使用了记忆辅助和策略来帮助支持日常记忆，这反过来又可以对患者和照顾者的结果产生积极影响。通过使用有助于编码和/或检索信息的记忆辅助和策略，可以为 PCA 提供类似的支持，但目前尚无适用于 PCA 的记忆策略指南。由于 PCA 定义了中央视觉障碍，因此在提出建议时需要仔细考虑。
将对已评估 AD 患者和相关痴呆症中记忆辅助和策略的发表研究进行范围综述，其中记忆被认为是核心或补充特征，目的是区分那些可能适合或适合 PCA 的特征。系统搜索将包括电子数据库 MEDLINE、PsycINFO 和 CINAHL，使用试点搜索中确定的痴呆症和记忆辅助和策略的搜索词。将根据使用的方法、人群、临床数据和识别出的记忆辅助和策略对发现进行映射和描述。
范围综述将概述 AD 患者和相关痴呆症中使用的记忆辅助和策略，并确定其特征、模式和语用学，以评估其对 PCA 人群的适用性和适应性。为 PCA 患者量身定制的记忆支持策略可以改善记忆表现，对患者和照顾者的结果产生积极影响。
