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spaced Retrieval 和 episodic Memory Training 在 Alzheimer 疾病中。

Spaced Retrieval and Episodic Memory Training in Alzheimer's Disease.

机构信息

School of Audiology and Speech Sciences, University of British Columbia, Vancouver, BC, Canada.

出版信息

Clin Interv Aging. 2020 Apr 17;15:519-536. doi: 10.2147/CIA.S242113. eCollection 2020.

Abstract

INTRODUCTION

This study replicated and extended the findings from the author's previous pilot study to further explore how a spaced retrieval (SR) memory training program might be effectively applied to help persons with Alzheimer's disease (AD)  improve both short- and long-term recall of recent episodic events.

METHODS

A quasi-experimental within-subject group study was conducted with 15 participants with a diagnosis of AD.

RESULTS

Compared to a control condition, all participants were able to spontaneously recall significantly more specific details about trained events, and their recall was significantly enhanced when they were provided with cues. Although the findings indicated that people with AD were able to encode information during training, recall gains diminished by the end of the maintenance period.

DISCUSSION

This study provides evidence that individuals with mild to moderate AD can learn and recall new episodic information through SR training. These findings support the use of SR as an intervention tool to help individuals maintain their functioning in episodic recent memory. However, more research into maintaining the long-term recall of recent episodic events is warranted.

摘要

简介

本研究复制并扩展了作者之前的初步研究结果,进一步探讨了如何有效地应用间隔检索(SR)记忆训练程序来帮助阿尔茨海默病(AD)患者改善近期情景事件的短期和长期回忆。

方法

采用 15 名 AD 诊断患者的准实验性被试内组研究。

结果

与对照组相比,所有参与者都能够自发地回忆起关于训练事件的更多具体细节,当他们提供线索时,他们的回忆得到了显著增强。尽管研究结果表明 AD 患者在训练过程中能够编码信息,但在维持期结束时,回忆的增益会减少。

讨论

本研究提供了证据表明,轻度至中度 AD 个体可以通过 SR 训练学习和回忆新的情景信息。这些发现支持将 SR 作为一种干预工具,帮助个体维持情景记忆的功能。然而,需要进一步研究如何保持对近期情景事件的长期回忆。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3662/7174872/24b32fc12227/CIA-15-519-g0001.jpg

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