• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Editorial: Advances in bioprocessing of viral vectors and virus-like particles.

作者信息

Vormittag Philipp, Wolff Michael W

机构信息

Lonza AG/Ltd, Drug Product Services, Basel, Switzerland.

Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen (THM), Giessen, Germany.

出版信息

Front Bioeng Biotechnol. 2023 Mar 14;11:1166430. doi: 10.3389/fbioe.2023.1166430. eCollection 2023.

DOI:10.3389/fbioe.2023.1166430
PMID:36998809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10043472/
Abstract
摘要

相似文献

1
Editorial: Advances in bioprocessing of viral vectors and virus-like particles.社论：病毒载体和病毒样颗粒生物加工的进展
Front Bioeng Biotechnol. 2023 Mar 14;11:1166430. doi: 10.3389/fbioe.2023.1166430. eCollection 2023.
2
Advancements in molecular design and bioprocessing of recombinant adeno-associated virus gene delivery vectors using the insect-cell baculovirus expression platform.利用昆虫细胞杆状病毒表达平台进行重组腺相关病毒基因传递载体的分子设计和生物加工的进展。
Biotechnol J. 2021 Apr;16(4):e2000021. doi: 10.1002/biot.202000021. Epub 2021 Jan 25.
3
Virus-like particle and viral vector production using the baculovirus expression vector system/insect cell system: adeno-associated virus-based products.使用杆状病毒表达载体系统/昆虫细胞系统生产病毒样颗粒和病毒载体：基于腺相关病毒的产品。
Methods Mol Biol. 2007;388:281-96. doi: 10.1007/978-1-59745-457-5_14.
4
Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System.杆状病毒表达载体系统提高病毒样颗粒的生产效率
PLoS One. 2015 Oct 12;10(10):e0140039. doi: 10.1371/journal.pone.0140039. eCollection 2015.
5
Evaluation of Virus-Free Manufacture of Recombinant Proteins Using CRISPR-Mediated Gene Disruption in Baculovirus-Infected Insect Cells.利用CRISPR介导的基因破坏在杆状病毒感染的昆虫细胞中无病毒生产重组蛋白的评估。
Vaccines (Basel). 2023 Jan 19;11(2):225. doi: 10.3390/vaccines11020225.
6
[Progress in vaccine development based on baculovirus expression vector system].[基于杆状病毒表达载体系统的疫苗开发进展]
Sheng Wu Gong Cheng Xue Bao. 2019 Apr 25;35(4):577-588. doi: 10.13345/j.cjb.180301.
7
Targeted supplementation design for improved production and quality of enveloped viral particles in insect cell-baculovirus expression system.在昆虫细胞-杆状病毒表达系统中，为提高包膜病毒颗粒的产量和质量而进行的靶向补充设计。
J Biotechnol. 2016 Sep 10;233:34-41. doi: 10.1016/j.jbiotec.2016.06.029. Epub 2016 Jul 1.
8
Overview of the Baculovirus Expression System.杆状病毒表达系统概述。
Curr Protoc Protein Sci. 2018 Feb 21;91:5.4.1-5.4.6. doi: 10.1002/cpps.47.
9
Utility of Alternative Promoters for Foreign Gene Expression Using the Baculovirus Expression Vector System.利用杆状病毒表达载体系统的替代启动子进行外源基因表达的效用。
Viruses. 2022 Nov 29;14(12):2670. doi: 10.3390/v14122670.
10
VLP-factory™ and ADDomer : Self-assembling Virus-Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display.VLP- 工厂™ 和 ADDomer：用于多种蛋白质和肽表位展示的自组装病毒样颗粒 (VLP) 技术。
Curr Protoc. 2021 Mar;1(3):e55. doi: 10.1002/cpz1.55.

本文引用的文献

1
Quantification methods for viruses and virus-like particles applied in biopharmaceutical production processes.生物制药生产过程中应用的病毒和病毒样颗粒的定量方法。
Expert Rev Vaccines. 2022 Aug;21(8):1029-1044. doi: 10.1080/14760584.2022.2072302. Epub 2022 May 6.
2
HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral Vectors.HEK293细胞系作为生产重组蛋白和病毒载体的平台。
Front Bioeng Biotechnol. 2021 Dec 13;9:796991. doi: 10.3389/fbioe.2021.796991. eCollection 2021.
3
Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography.采用伪亲和膜色谱法连续纯化流感 A 病毒颗粒。
J Biotechnol. 2021 Dec 10;342:139-148. doi: 10.1016/j.jbiotec.2021.10.003. Epub 2021 Oct 20.
4
Process development for cross-flow diafiltration-based VLP disassembly: A novel high-throughput screening approach.基于切向流超滤的病毒样颗粒拆解的工艺开发：一种新型高通量筛选方法。
Biotechnol Bioeng. 2021 Oct;118(10):3926-3940. doi: 10.1002/bit.27868. Epub 2021 Jul 10.
5
Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection.用于预防严重急性呼吸综合征冠状病毒 2 感染的临床开发疫苗制剂。
Adv Drug Deliv Rev. 2021 Feb;169:168-189. doi: 10.1016/j.addr.2020.12.006. Epub 2020 Dec 13.
6
A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applications.一种可扩展的下游工艺，用于纯化细胞培养来源的 Orf 病毒，用于人类或兽医应用。
J Biotechnol. 2020 Nov 10;323:221-230. doi: 10.1016/j.jbiotec.2020.08.014. Epub 2020 Aug 27.
7
Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration.病毒样颗粒捕获与纯化的集成工艺：通过错流过滤提高工艺性能
Front Bioeng Biotechnol. 2020 May 25;8:489. doi: 10.3389/fbioe.2020.00489. eCollection 2020.
8
Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers.使用硫酸化纤维素膜吸附剂优化细胞培养衍生的甲型流感病毒颗粒的纯化
Eng Life Sci. 2017 Oct 16;18(1):29-39. doi: 10.1002/elsc.201700108. eCollection 2018 Jan.
9
Ensembles of Hydrophobicity Scales as Potent Classifiers for Chimeric Virus-Like Particle Solubility - An Amino Acid Sequence-Based Machine Learning Approach.疏水标度集合作为嵌合病毒样颗粒溶解度的有效分类器——一种基于氨基酸序列的机器学习方法
Front Bioeng Biotechnol. 2020 May 5;8:395. doi: 10.3389/fbioe.2020.00395. eCollection 2020.
10
Overview of the Baculovirus Expression System.杆状病毒表达系统概述。
Curr Protoc Protein Sci. 2018 Feb 21;91:5.4.1-5.4.6. doi: 10.1002/cpps.47.