Zeng Yi, Chen Lu-Chuan, Ye Zai-Sheng, Deng Jing-Yu
Department of Gastrointestinal Surgical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou 350014, Fujian Province, China.
Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300202, China.
World J Clin Cases. 2023 Mar 26;11(9):1930-1938. doi: 10.12998/wjcc.v11.i9.1930.
Lymph node (LN) metastasis is the most common form of metastasis in gastric cancer (GC). The status and stage of LN metastasis are important indicators that reflect the progress of GC. The number of LN metastases is still the most effective index to evaluate the prognosis of patients in all stages of LN metastasis. Examined LN (ELN) count refers to the number of LNs harvested from specimens by curative gastrectomy for pathological examination. This review summarizes the factors that influence ELN count, including individual and tumor factors, intraoperative dissection factors, postoperative sorting factors, and pathological examination factors. Different ELN counts will lead to prognosis-related stage migration. Fine LN sorting and regional LN sorting are the two most important LN sorting technologies. The most direct and effective way to harvest a large number of LNs is for surgeons to perform fine LN sorting.
淋巴结（LN）转移是胃癌（GC）最常见的转移形式。LN转移的状态和阶段是反映GC进展的重要指标。LN转移数量仍然是评估LN转移各阶段患者预后的最有效指标。检查的淋巴结（ELN）计数是指通过根治性胃切除术从标本中获取用于病理检查的淋巴结数量。本综述总结了影响ELN计数的因素，包括个体和肿瘤因素、术中清扫因素、术后分拣因素以及病理检查因素。不同的ELN计数会导致与预后相关的分期迁移。精细淋巴结分拣和区域淋巴结分拣是两种最重要的淋巴结分拣技术。外科医生进行精细淋巴结分拣是获取大量淋巴结的最直接有效方法。
