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机器人胃癌根治术中吲哚菁绿(ICG)的应用:胃癌淋巴结清扫结果的回顾性分析

Indocyanine Green (ICG) in Robotic Gastrectomy: A Retrospective Review of Lymphadenectomy Outcomes for Gastric Cancer.

作者信息

Jeon Chul-Hyo, Kim So-Jung, Lee Han-Hong, Song Kyo-Young, Seo Ho-Seok

机构信息

Division of Gastrointestinal Surgery, Department of Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Gyeonggi-do 11765, Republic of Korea.

Division of Trauma and Surgical Critical Care, Department of Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Gyeonggi-do 11765, Republic of Korea.

出版信息

Cancers (Basel). 2023 Oct 11;15(20):4949. doi: 10.3390/cancers15204949.

Abstract

Radical gastrectomy is essential for gastric cancer treatment. While guidelines advise dissecting at least 16 lymph nodes, some research suggests over 30 nodes might be beneficial. This study assessed ICG-guided robotic gastrectomy's effectiveness in thorough lymph node dissection. We analyzed data from 393 stage II or III gastric cancer patients treated at Seoul St. Mary's Hospital from 2016-2022. Patients were categorized into conventional laparoscopy (G1, = 288), ICG-guided laparoscopy (G2, = 61), and ICG-guided robotic surgery (G3, = 44). Among 391 patients, 308 (78.4%) achieved proper lymphadenectomy. The ICG-robotic group (G3) showed the highest success rate at 90.9%. ICG-guided robotic surgery was a significant predictor for achieving proper lymphadenectomy, with an odds ratio of 3.151. In conclusion, ICG-robotic gastrectomy improves lymphadenectomy outcomes in selected gastric cancer cases, indicating a promising surgical approach for the future.

摘要

根治性胃切除术是胃癌治疗的关键。虽然指南建议至少清扫16个淋巴结,但一些研究表明清扫超过30个淋巴结可能更有益。本研究评估了吲哚菁绿(ICG)引导下机器人胃切除术在彻底淋巴结清扫方面的有效性。我们分析了2016年至2022年在首尔圣母医院接受治疗的393例II期或III期胃癌患者的数据。患者被分为传统腹腔镜手术组(G1组,n = 288)、ICG引导下腹腔镜手术组(G2组,n = 61)和ICG引导下机器人手术组(G3组,n = 44)。在391例患者中,308例(78.4%)实现了恰当的淋巴结切除术。ICG机器人手术组(G3组)的成功率最高,为90.9%。ICG引导下机器人手术是实现恰当淋巴结切除术的显著预测因素,比值比为3.151。总之,ICG机器人胃切除术在特定胃癌病例中改善了淋巴结清扫结果,表明这是一种未来有前景的手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8381/10605643/7913c287f00c/cancers-15-04949-g001.jpg

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