Clin Nephrol. 2023 Jun;99(6):290-298. doi: 10.5414/CN111038.
To evaluate the formation of encrustation on double J stents (DJSs) using artificial urine.
In this study, a static urinary system containing artificial urine was created, and a total of 45 DJSs were used to evaluate the formation of encrustation. Three groups of 15 DJSs were tested for 4, 8, or 14 weeks. The formation of encrustation on the DJSs over the weeks was analyzed using methods including X-ray powder diffraction (XRD), inductively coupled plasma spectrophotometer (ICP), and scanning electron microscope (SEM). Statistical analysis and the uncertainty test were used for data analysis using R language.
The ICP analyzed the weight of the calcium and magnesium, which are the major components of urinary stones and encrustation, and showed that it was the heaviest at 14 weeks. Measurement of the area of encrustation on the outer surface of the DJSs revealed that the encrustation area at the bottom of the stent was greater than that at the top of the stent, regardless of the experimental period (proximal part: ≤ 41,099 µm, distal part: ≤ 183,259 µm). Encrustation occurred around the side holes of DJSs and became bigger over time to fill up the side holes.
Encrustation spots included the bottom zone of the DJS and around the side holes. These results indicate that the performance of DJSs would be improved by modifying the shape of DJSs located near the bladder and side holes.
使用人工尿液评估双 J 支架（DJS）上结石的形成。
本研究创建了一个包含人工尿液的静态泌尿系统，共使用 45 个 DJS 来评估结石的形成。三组各有 15 个 DJS 分别测试 4、8 或 14 周。使用 X 射线粉末衍射（XRD）、电感耦合等离子体分光光度计（ICP）和扫描电子显微镜（SEM）分析了 DJS 上结石形成的情况。使用 R 语言对数据进行统计分析和不确定度测试。
ICP 分析了钙和镁的重量，它们是结石和结石的主要成分，在 14 周时最重。DJS 外表面结石面积的测量表明，支架底部的结石面积大于支架顶部的结石面积，无论实验周期如何（近端：≤41099µm，远端：≤183259µm）。结石在 DJS 的侧孔周围形成，并随时间推移而变大，填满侧孔。
结石点包括 DJS 的底部区域和侧孔周围。这些结果表明，通过修改膀胱和侧孔附近 DJS 的形状，可以提高 DJS 的性能。
