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一种新型在线综合治疗方案对赌博和吸烟问题的疗效:一项随机对照试验的结果。

Efficacy of a novel online integrated treatment for problem gambling and tobacco smoking: Results of a randomized controlled trial.

机构信息

1Department of Psychology, University of Manitoba, Canada.

2Swiss Research Institute for Public Health and Addiction, University of Zurich, Switzerland.

出版信息

J Behav Addict. 2023 Feb 22;12(1):168-181. doi: 10.1556/2006.2022.00081. Print 2023 Mar 30.

Abstract

BACKGROUND AND AIMS

Problem gambling and tobacco use are highly comorbid among adults. However, there are few treatment frameworks that target both gambling and tobacco use simultaneously (i.e., an integrated approach), while also being accessible and evidence-based. The aim of this two-arm open label RCT was to examine the efficacy of an integrated online treatment for problem gambling and tobacco use.

METHODS

A sample of 209 participants (Mage = 37.66, SD = 13.81; 62.2% female) from North America were randomized into one of two treatment conditions (integrated [n = 91] or gambling only [n = 118]) that lasted for eight weeks and consisted of seven online modules. Participants completed assessments at baseline, after treatment completion, and at 24-week follow-up.

RESULTS

While a priori planned generalized linear mixed models showed no condition differences on primary (gambling days, money spent, time spent) and secondary outcomes, both conditions did appear to significantly reduce problem gambling and smoking behaviours over time. Post hoc analyses showed that reductions in smoking and gambling craving were correlated with reductions in days spent gambling, as well as with gambling disorder symptoms. Relatively high (versus low) nicotine replacement therapy use was associated with greater reductions in gambling behaviours in the integrated treatment condition.

DISCUSSION AND CONCLUSIONS

While our open label RCT does not support a clear benefit of integrated treatment, findings suggest that changes in smoking and gambling were correlated over time, regardless of treatment condition, suggesting that more research on mechanisms of smoking outcomes in the context of gambling treatment may be relevant.

摘要

背景与目的

赌博问题和烟草使用在成年人中高度共病。然而,针对赌博和烟草使用同时进行治疗的治疗框架(即综合方法)很少,而且还需要具有可及性和基于证据。本两项臂开放式标签 RCT 的目的是检验一种针对赌博问题和烟草使用的综合在线治疗的疗效。

方法

一项来自北美的 209 名参与者(Mage = 37.66,SD = 13.81;62.2%女性)的样本被随机分配到两种治疗条件之一(综合治疗[n = 91]或仅赌博治疗[n = 118]),治疗持续八周,包括七个在线模块。参与者在基线、治疗完成后和 24 周随访时完成评估。

结果

虽然预先计划的广义线性混合模型显示主要(赌博天数、花费金额、花费时间)和次要结局在条件之间没有差异,但两种条件似乎都随着时间的推移显著减少了赌博问题和吸烟行为。事后分析表明,吸烟和赌博欲望的减少与赌博天数的减少以及赌博障碍症状的减少相关。相对较高(相对于较低)尼古丁替代疗法的使用与综合治疗条件下赌博行为的更大减少相关。

讨论与结论

虽然我们的开放式标签 RCT 并不支持综合治疗的明显益处,但研究结果表明,无论治疗条件如何,吸烟和赌博的变化随着时间的推移都是相关的,这表明在赌博治疗背景下对吸烟结果的机制进行更多研究可能是相关的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0bd/10260216/f138e0ada9b3/jba-12-168-g001.jpg

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