School of Computer Science, South China Normal University, Guangzhou, China.
Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Neural Netw. 2023 May;162:571-580. doi: 10.1016/j.neunet.2023.03.019. Epub 2023 Mar 21.
Sleep apnea (SA) is a common sleep-related breathing disorder, which would lead to damage of multiple systemic organs or even sudden death. In clinical practice, portable device is an important tool to monitor sleep conditions and detect SA events by using physiological signals. However, SA detection performance is still limited due to physiological signals with time-variability and complexity. In this paper, we focus on SA detection with single lead ECG signals, which can be easily collected by a portable device. Under this context, we propose a restricted attention fusion network called RAFNet for sleep apnea detection. Specifically, RR intervals (RRI) and R-peak amplitudes (Rpeak) are generated from ECG signals and divided into one-minute-long segments. To alleviate the problem of insufficient feature information of the target segment, we combine the target segment with two pre- and post-adjacent segments in sequence, (i.e. a five-minute-long segment), as the input. Meanwhile, by leveraging the target segment as the query vector, we propose a new restricted attention mechanism with cascaded morphological and temporal attentions, which can effectively learn the feature information and depress redundant feature information from the adjacent segments with adaptive assigning weight importance. To further improve the SA detection performance, the target and adjacent segment features are fused together with the channel-wise stacking scheme. Experiment results on the public Apnea-ECG dataset and the real clinical FAH-ECG dataset with sleep apnea annotations show that the RAFNet greatly improves SA detection performance and achieves competitive results, which are superior to those achieved by the state-of-the-art baselines.
睡眠呼吸暂停(SA)是一种常见的与睡眠相关的呼吸障碍,可导致多个系统器官受损,甚至猝死。在临床实践中,便携式设备是通过生理信号监测睡眠状况和检测 SA 事件的重要工具。然而,由于生理信号具有时变性和复杂性,SA 检测性能仍然有限。在本文中,我们专注于使用单导联心电图信号(ECG 信号)进行 SA 检测,该信号可以通过便携式设备轻松采集。在这种情况下,我们提出了一种称为 RAFNet 的受限注意力融合网络,用于睡眠呼吸暂停检测。具体来说,从 ECG 信号中生成 RR 间隔(RRI)和 R 波峰值幅度(Rpeak),并将其分为一分钟长的片段。为了缓解目标片段特征信息不足的问题,我们按顺序将目标片段与两个前导和后续片段(即五分钟长的片段)组合,作为输入。同时,通过利用目标片段作为查询向量,我们提出了一种新的受限注意力机制,具有级联形态和时间注意力,可以有效地从相邻片段中学习特征信息,并通过自适应分配权重重要性来抑制冗余特征信息。为了进一步提高 SA 检测性能,目标和相邻片段特征通过通道堆叠方案融合在一起。在具有睡眠呼吸暂停注释的公共 Apnea-ECG 数据集和真实临床 FAH-ECG 数据集上的实验结果表明,RAFNet 大大提高了 SA 检测性能,并取得了有竞争力的结果,优于最先进的基线方法。