King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs (MNG-HA), Riyadh, Saudi Arabia.
Department of Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
J Genet Couns. 2023 Oct;32(5):1032-1039. doi: 10.1002/jgc4.1713. Epub 2023 Apr 2.
In this cross-sectional study, we assessed the attitudes of the general public in Saudi Arabia regarding both medical and non-medical applications of pre-implantation genetic diagnosis (PGD). The study was conducted in King Abdullah Specialist Children's Hospital (KASCH) in Riyadh with a sample size of 377. Demographic information was collected, and attitudes towards applications of PGD were assessed using a pre-validated self-administered questionnaire. Out of the total sample size, 230 (61%) were males, 258 (68%) were married, 235 (63%) had one child or more, and 255 (68%) were older than 30 years of age representing the majority of participants. Only 87 (23%) of participants reported prior experience with PGD. Personally, knowing someone who had a prior experience with PGD was associated with higher attitude scores (more favorable attitudes towards PGD) (p-value = 0.04). The findings of this study indicate that our sample of Saudi individuals generally had a positive attitude towards the use of PGD.
在这项横断面研究中，我们评估了沙特阿拉伯公众对植入前遗传学诊断（PGD）的医学和非医学应用的态度。该研究在利雅得的阿卜杜拉国王专科儿童医院（KASCH）进行，样本量为 377 人。收集了人口统计学信息，并使用预先验证的自我管理问卷评估了对 PGD 应用的态度。在总样本量中，230 名（61%）为男性，258 名（68%）已婚，235 名（63%）有一个或多个孩子，255 名（68%）年龄大于 30 岁，占大多数参与者。只有 87 名（23%）的参与者报告了之前有过 PGD 经验。个人方面，了解有人有过 PGD 经验与更高的态度评分（对 PGD 更有利的态度）相关（p 值=0.04）。这项研究的结果表明，我们的沙特个体样本普遍对 PGD 的使用持积极态度。
