辐射损伤防护剂的研究进展

[Research progress of irradiation injuries anti-agents].

作者信息

Du Y N, Yang X Y, Zeng Q

机构信息

Institute for Occupational Health, Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2023 Mar 20;41(3):237-240. doi: 10.3760/cma.j.cn121094-20210813-00396.

DOI:10.3760/cma.j.cn121094-20210813-00396

PMID:37006154

Abstract

Irradiation injuries anti-agents refer to drugs that can inhibit the initial stage of radiation injuries, or reduce the development of radiation injuries and promote the recovery of injuries when used early after irradiation exposure. According to the mechanism of action and the time of intervention, the irradiation injuries anti-agents are divided into four categories: radioprotectors, radiomitigators, radiation therapeutics for external radiation exposure, and anti-agents for internalized radionuclides. In this paper, the research progress of irradiation injuries anti-agents in recent years is reviewed.

摘要

辐射损伤抗剂是指能抑制辐射损伤初期，或在照射后早期使用时减少辐射损伤发展并促进损伤恢复的药物。根据作用机制和干预时间，辐射损伤抗剂分为四类：辐射防护剂、辐射缓解剂、外照射辐射治疗剂和内摄入放射性核素抗剂。本文综述了近年来辐射损伤抗剂的研究进展。