Wang Yan, Sun Kaiyuan, Pan Yang, Yi Lan, Huo Da, Wu Yanpeng, Dong Shuaibing, Guo Jinxin, Dou Xiangfeng, Wang Wei, Wu Shuangsheng, Bai Xufang, Yu Hongjie, Wang Quanyi
School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai Municipality, China.
Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
China CDC Wkly. 2023 Feb 3;5(5):108-112. doi: 10.46234/ccdcw2023.020.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: China has repeatedly contained multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks through a comprehensive set of targeted non-pharmaceutical interventions (NPIs). However, the effectiveness of such NPIs has not been systematically assessed.
WHAT IS ADDED BY THIS REPORT?: A multilayer deployment of case isolation, contact tracing, targeted community lockdowns, and mobility restrictions could potentially contain outbreaks caused by the SARS-CoV-2 ancestral strain, without the requirement of city-wide lockdowns. Mass testing could further aid in the efficacy and speed of containment.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Pursuing containment in a timely fashion at the beginning of the pandemic, before the virus had the opportunity to spread and undergo extensive adaptive evolution, could help in averting an overall pandemic disease burden and be socioeconomically cost-effective.
关于该主题已知的信息有哪些？：中国通过一系列全面的针对性非药物干预措施（NPIs）多次控制住了多起严重急性呼吸综合征冠状病毒2（SARS-CoV-2）疫情。然而，此类非药物干预措施的有效性尚未得到系统评估。
本报告新增了哪些内容？：对病例隔离、接触者追踪、针对性社区封锁和流动限制进行多层次部署，有可能控制由SARS-CoV-2原始毒株引发的疫情，而无需实施全市范围的封锁。大规模检测可进一步提高控制疫情的效果和速度。
对公共卫生实践有何启示？：在疫情初期，趁病毒尚未有机会传播并经历广泛适应性进化之时及时采取控制措施，有助于避免整体的大流行疾病负担，并在社会经济方面具有成本效益。
