Fedorova Tatyana D, Knudsen Karoline, Rasmussen Thorsten K, Horsager Jacob, Nahimi Adjmal, Skjærbæk Casper, Schaeffer Eva, Berg Daniela, Terkelsen Astrid J, Borghammer Per
Aarhus University Hospital, Department of Nuclear Medicine and PET Centre, Aarhus, Denmark.
Aarhus University, Dept. of Clinical Medicine, Aarhus, Denmark.
IBRO Neurosci Rep. 2023 Mar 21;14:342-345. doi: 10.1016/j.ibneur.2023.03.006. eCollection 2023 Jun.
Thyroid [I]MIBG uptake is proposed as a tool for differentiating between Parkinson's disease (PD) and diabetes mellitus (DM) on [I]MIBG scintigraphies since both patient groups show decreased cardiac uptake. One study compared thyroid [I]MIBG uptake in DM and PD patients and reported reduced [I]MIBG uptake only in the PD group. Here, we investigated thyroid [I]MIBG uptake in patients with PD and DM and found severely reduced thyroid [I]MIBG uptake in DM. Larger studies are needed to substantiate whether DM patients are more or less likely to exhibit decreased thyroid MIBG uptake compared to controls and PD patients.
甲状腺[I]间碘苄胍摄取被提议作为一种在[I]间碘苄胍闪烁扫描中区分帕金森病（PD）和糖尿病（DM）的工具，因为这两组患者的心脏摄取均降低。一项研究比较了糖尿病患者和帕金森病患者的甲状腺[I]间碘苄胍摄取情况，报告称仅帕金森病组的[I]间碘苄胍摄取降低。在此，我们研究了帕金森病患者和糖尿病患者的甲状腺[I]间碘苄胍摄取情况，发现糖尿病患者的甲状腺[I]间碘苄胍摄取严重降低。需要开展更大规模的研究来证实与对照组和帕金森病患者相比，糖尿病患者甲状腺间碘苄胍摄取降低的可能性是更高还是更低。
IBRO Neurosci Rep. 2023-3-21
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