Khan Abdul Qayyum, Qamar Rayed, Chowdhry Madhav, Siddiqui Bushra, Khan Saad Mohammad, Gupta Divas
Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh 202002 India.
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh 202002 India.
Indian J Orthop. 2023 Feb 15;57(4):603-607. doi: 10.1007/s43465-023-00831-8. eCollection 2023 Apr.
Diffuse Large B-Cell Lymphoma (DLBCL) of bone is a rare presentation of Non-Hodgkin Lymphoma (NHL), which remains asymptomatic or present late in clinical course as bone pain or pathological fracture. We report a case of a 15-year-old male child presenting with diffuse joint pain and swelling over his left shoulder and elbow, associated with B symptoms. Radiological examination revealed lytic lesions in multiple bones along with collection along the left iliopsoas and hip joint, suggestive of infective etiology. The diagnostic dilemma was resolved on biopsy, which confirmed DLBCL involving bones and soft tissue.
骨弥漫性大B细胞淋巴瘤（DLBCL）是一种罕见的非霍奇金淋巴瘤（NHL）表现形式，在临床过程中通常无症状或出现较晚，表现为骨痛或病理性骨折。我们报告一例15岁男性儿童，表现为左肩和肘部弥漫性关节疼痛和肿胀，并伴有B症状。影像学检查显示多骨溶骨性病变以及左髂腰肌和髋关节处有积液，提示感染性病因。活检解决了诊断难题，证实为累及骨骼和软组织的DLBCL。
