Yamamoto Hideya, Fujimoto Shinichiro, Aoshima Chihiro, Minamino Tohru, Fujii Takashi, Wakabayashi Shinichi, Urabe Yoji, Ueda Hironori, Kunita Eiji, Abe Mitsunori, Higashino Hiroshi
Laboratory of Physiology and Morphology, School of Pharmacy, Yasuda Women's University, Hiroshima, Hiroshima, Japan.
Department of Cardiology, Suisei-kai Kajikawa Hospital, Hiroshima, Hiroshima, Japan.
Ann Vasc Dis. 2023 Mar 25;16(1):46-53. doi: 10.3400/avd.oa.22-00060.
We aimed to evaluate the visual measurements of coronary artery calcium (CAC) on nonelectrocardiogram (ECG)-gated chest computed tomography (CT) using a simple scoring method that involves counting the number of CT slices containing CAC. We analyzed 163 participants who underwent both coronary and chest CT examinations at six centers within 3 months. Agatston scores were calculated on standard ECG-gated scans and classified as none (0), mild (1-99), moderate (100-400), or severe (>400). Next, chest CT images were reconstructed to standard 5.0 mm axial slices. Then, CAC on chest CT scans was measured using two methods: the Weston score (sum of the assigned score of each vessel, range: 0-12) and number of slices showing CAC (Ca-slice#). When the Weston score and Ca-slice# were divided into four levels according to the optimal divisional levels corresponding to the Agatston score classes, good agreements with the 4-grade Agatston score were observed (kappa value=0.610 and 0.794, respectively). The sensitivity and specificity of Ca-slice# ≥9 to identify severe Agatston scores of >400 were 86% and 96%, respectively. The Ca-slice#, a simple scoring method using chest CT scans, was in good agreement with the ECG-gated Agatston score.
我们旨在使用一种简单的评分方法评估非心电图(ECG)门控胸部计算机断层扫描(CT)上冠状动脉钙化(CAC)的视觉测量,该方法包括计算包含CAC的CT切片数量。我们分析了163名在3个月内于六个中心接受冠状动脉和胸部CT检查的参与者。在标准ECG门控扫描上计算阿加斯顿评分,并将其分类为无(0)、轻度(1 - 99)、中度(100 - 400)或重度(>400)。接下来,将胸部CT图像重建为标准的5.0毫米轴向切片。然后,使用两种方法测量胸部CT扫描上的CAC:韦斯顿评分(每个血管指定分数的总和,范围:0 - 12)和显示CAC的切片数量(Ca-slice#)。当根据与阿加斯顿评分类别对应的最佳划分水平将韦斯顿评分和Ca-slice#分为四个级别时,观察到与4级阿加斯顿评分有良好的一致性(kappa值分别为0.610和0.794)。Ca-slice#≥9识别阿加斯顿评分>400的重度评分的敏感性和特异性分别为86%和96%。Ca-slice#是一种使用胸部CT扫描的简单评分方法,与ECG门控的阿加斯顿评分有良好的一致性。