Gupta Lalita, Soliman Mohamed Kamel, Ahmad Riaz, Kurup Shree
Department of Ophthalmology and Visual Sciences, University Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH, USA.
Department of Ophthalmology, Assiut University Hospitals, Assiut, Egypt.
J Vitreoretin Dis. 2021 Mar 5;5(6):542-545. doi: 10.1177/2474126421996261. eCollection 2021 Nov-Dec.
This work reports a case of systemic sarcoidosis presenting with ischemic ocular manifestations without uveitis.
This case report describes a 28-year-old White male who presented with pain, redness, and blurry vision of his left eye for 1 month who was found to have proliferative retinopathy and neovascular glaucoma.
Normal fasting blood glucose and glycated hemoglobin A levels warranted further investigation. Abnormal findings from chest x-ray of hilar lymphadenopathy as well as an elevated angiotensin-converting enzyme level were suggestive of sarcoidosis, and they were further confirmed by histopathology derived through bronchoscopy.
Systemic sarcoidosis may present with rapidly progressing ischemic retinopathy without signs of inflammation, which may obscure the diagnosis. Such presentation may be misdiagnosed, which may result in delayed treatment and poor outcome.
本研究报告了一例系统性结节病，表现为缺血性眼部表现但无葡萄膜炎。
本病例报告描述了一名28岁的白人男性，其左眼疼痛、发红和视力模糊1个月，被发现患有增殖性视网膜病变和新生血管性青光眼。
空腹血糖和糖化血红蛋白A水平正常，需要进一步检查。胸部X线显示肺门淋巴结肿大以及血管紧张素转换酶水平升高，提示结节病，并通过支气管镜检查获得的组织病理学进一步证实。
系统性结节病可能表现为迅速进展的缺血性视网膜病变而无炎症迹象，这可能会掩盖诊断。这种表现可能会被误诊，从而导致治疗延迟和预后不良。
