Hsu Fred
Radiation Oncology, BC Cancer-Abbotsford Centre, Abbotsford, CAN.
Cureus. 2023 Feb 28;15(2):e35592. doi: 10.7759/cureus.35592. eCollection 2023 Feb.
Jugular foramen tumours are uncommon, deeply located, and eloquently situated, making their diagnosis and management challenging. Paragangliomas and other benign tumours comprise the large majority of lesions in this region, but malignant tumours are occasionally identified. We report a unique case of a solitary plasmacytoma of the jugular foramen resembling a jugulotympanic paraganglioma. A solitary plasmacytoma of the jugular foramen is both rare in location and in disease presentation, as most plasma cell neoplasms are diagnosed as multiple myeloma. Our 75-year-old patient presented with symptoms typical for a jugular foramen tumour. Although there are radiographic features which help differentiate paragangliomas from other benign and malignant tumours, plasmacytomas are highly vascular and can demonstrate a local infiltrative spread which can mimic the radiographic appearance of a paraganglioma. Clinicians should consider plasma cell neoplasms in the differential when faced with an unusual presentation of a jugular foramen lesion. Our patient was treated with definitive radiotherapy to 45 Gy, which was very effective local treatment for the solitary plasmacytoma.
颈静脉孔区肿瘤并不常见，位置较深且毗邻重要结构，这使得其诊断和治疗颇具挑战性。副神经节瘤和其他良性肿瘤占该区域病变的绝大多数，但偶尔也会发现恶性肿瘤。我们报告了一例罕见的颈静脉孔区孤立性浆细胞瘤，其表现类似颈静脉鼓室副神经节瘤。颈静脉孔区孤立性浆细胞瘤在发病部位和临床表现上均较为罕见，因为大多数浆细胞肿瘤被诊断为多发性骨髓瘤。我们的75岁患者表现出典型的颈静脉孔区肿瘤症状。尽管有影像学特征有助于鉴别副神经节瘤与其他良性和恶性肿瘤，但浆细胞瘤血管丰富，可表现为局部浸润性生长，其影像学表现可类似于副神经节瘤。临床医生在面对颈静脉孔区病变的不寻常表现时，应在鉴别诊断中考虑浆细胞肿瘤。我们的患者接受了45 Gy的根治性放疗，这对孤立性浆细胞瘤是非常有效的局部治疗。
