Kapetanakis Stylianos, Chourmouzi Danai, Gkasdaris Grigorios, Katsaridis Vasileios, Eleftheriadis Eleftherios, Givissis Panagiotis
Spine Department and Deformities, Interbalkan European Medical Center, Thessaloniki, Greece.
Radiology Department, Interbalkan European Medical Center, Thessaloniki, Greece.
J Surg Case Rep. 2018 Feb 3;2018(2):rjy005. doi: 10.1093/jscr/rjy005. eCollection 2018 Feb.
Paragangliomas are benign neoplasms that arise from the autonomic nervous system and the associated paraganglia. Although benign, they have been shown to possess metastatic potential. Involvement of the spine is rare. Even rarer is considered the involvement of the cervical spine. We report a case of a patient with a history of an extra-adrenal non-functional paraganglioma of the jugular foramen which was initially treated with intra-arterial embolization. After a 3-year disease-free follow-up, the patient was presented with symptoms of spinal cord compression due to spinal metastases in C2 and C3 vertebrae. The patient was then treated with surgical decompression and external beam radiation. Therapeutic management with additional treatment options is now under discussion by a multidisciplinary team. Paraganglioma of the jugular foramen with spinal metastasis is an uncommon presentation where increased physician awareness and long-term follow-up are mandatory for all patients with history of paraganglioma.
副神经节瘤是起源于自主神经系统和相关副神经节的良性肿瘤。尽管是良性的，但已显示它们具有转移潜能。脊柱受累情况罕见。颈椎受累则更为罕见。我们报告一例患者，有颈静脉孔区肾上腺外无功能副神经节瘤病史，最初接受动脉内栓塞治疗。在3年无病随访后，患者因C2和C3椎体的脊柱转移出现脊髓受压症状。随后患者接受了手术减压和外照射放疗。一个多学科团队正在讨论采用其他治疗方案的治疗管理。颈静脉孔区副神经节瘤伴脊柱转移是一种不常见的表现，对于所有有副神经节瘤病史的患者，提高医生的认识和进行长期随访是必不可少的。
