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手术引流后慢性硬膜下血肿的临床结局及复发风险

Clinical Outcome and Recurrence Risk of Chronic Subdural Hematoma After Surgical Drainage.

作者信息

Atefi Negar, Alcock Susan, Silvaggio Joseph A, Shankar Jai

机构信息

Department of Radiology, Max Rady College of Medicine, University of Manitoba, Winnipeg, CAN.

Department of Internal Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, CAN.

出版信息

Cureus. 2023 Feb 27;15(2):e35525. doi: 10.7759/cureus.35525. eCollection 2023 Feb.

Abstract

Introduction Chronic subdural hematoma (CSDH) is one of the most encountered neurosurgical cases. CSDH is defined as the accumulation of liquified blood products in the space between the dura and the arachnoid. A reported incidence of 17.6/100,000/year has more than doubled in the past 25 years in parallel with an aging population. Surgical drainage remains the mainstay of treatment, yet it is challenged by variable recurrence risks. Less invasive embolization methods of the middle meningeal artery (EMMA) could reduce the recurrence risks. Before adopting a newer treatment (EMMA), it is prudent to establish the outcomes from surgical drainage. The purpose of this study is to assess the clinical outcome and recurrence risk in surgically treated CSDH patients in our center. Methods A retrospective search of our surgical database was done to identify CSDH patients undergoing surgical drainage in the year 2019-2020. Demographic and clinical details were collected, and quantitative statistical analysis was performed. Peri-procedural radiographic information and follow-ups were also included as per the standard of care. Results A total of 102 patients (mean age: 69 years; range: 21-100 years; male: 79) with CSDH underwent surgical drainage with repeat surgery in 13.7% of the patients (n=14). Peri-procedural mortality and morbidity were 11.8%(n=12) and 19.6% (n=20), respectively. Overall, among our patient population, recurrence was seen in 22.55% (n=23). The mean total hospital stay was 10.6 days. Conclusions Our retrospective cohort study showed an institutional CSDH recurrence risk of 22.55%, in keeping with what is reported in the literature. This baseline information is important for a Canadian setting and provides a basis for comparison for future Canadian trials.

摘要

引言 慢性硬膜下血肿(CSDH)是神经外科最常见的病例之一。CSDH被定义为硬脑膜和蛛网膜之间间隙中液化血液产物的积聚。据报道,其发病率为每年17.6/10万,在过去25年中随着人口老龄化增加了一倍多。手术引流仍然是主要的治疗方法,但面临着不同的复发风险挑战。脑膜中动脉的微创栓塞方法(EMMA)可以降低复发风险。在采用更新的治疗方法(EMMA)之前,谨慎地确定手术引流的结果是明智的。本研究的目的是评估我院接受手术治疗的CSDH患者的临床结局和复发风险。方法 对我院手术数据库进行回顾性检索,以确定2019年至2020年接受手术引流的CSDH患者。收集人口统计学和临床细节,并进行定量统计分析。按照护理标准,还纳入了围手术期影像学信息和随访情况。结果 共有102例CSDH患者(平均年龄:69岁;范围:21 - 100岁;男性:79例)接受了手术引流,13.7%(n = 14)的患者接受了再次手术。围手术期死亡率和发病率分别为11.8%(n = 12)和19.6%(n = 20)。总体而言,在我们的患者群体中,复发率为22.55%(n = 23)。平均总住院天数为10.6天。结论 我们的回顾性队列研究显示,我院CSDH的复发风险为22.55%,与文献报道一致。这一基线信息对于加拿大的情况很重要,并为未来加拿大的试验提供了比较基础。

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