Choudhary Amruta, Inamdar Saunitra A, Sharma Urvashi
Department of Obstetrics and Gynaecology, Datta Meghe Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Nagpur, IND.
Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Medical Institute of Science (Deemed to be University), Wardha, IND.
Cureus. 2023 Feb 27;15(2):e35513. doi: 10.7759/cureus.35513. eCollection 2023 Feb.
Uterine fibroids are the most frequent benign tumor of the female reproductive system, with a significantly lower frequency in pregnancy. This could be due to the fact that uterine fibroids are linked to infertility and low implantation rates following in vitro fertilization (IVF). The goal of this study was to look at the obstetrics outcomes of uterine fibroids and their consequences in a tertiary hospital.
The current study was a observational cohort study that evaluated the cases of pregnancy with fibroid. Study was undertaken at the Department of Obstetrics and Gynecology (OBGY) at a medical college in central India and it was conducted over a period of nine months from 1st November 2021 to 31st July 2022. All pregnant women who had an ultrasonography (USG)-documented uterine fibroid diagnosed prenatally or antenatally were enrolled. All demographic information, laboratory and USG results were noted and their mode of delivery, obstetric complications, if any, and neonatal outcomes were evaluated.
A total of 110 cases were enrolled as per inclusion and exclusion criteria. The majority of patients (42.73%) were in the 26- to 30-year-old age group. In this study, the majority of cases were carried to term (80.9%). The most prevalent mode of delivery was caesarean section (61.82%). Major complications during pregnancy were threatened preterm labor (21.82%), and blood transfusion (20.00%), whereas postpartum hemorrhage (PPH) occurred in 9.09% cases, and 47 patients (42.72%) were asymptomatic throughout pregnancy. Major neonatal outcomes in our study were neonatal intensive care unit (NICU) hospitalization (20%), required neonatal resuscitation (14.55%), and neonatal mortality occurring in 1.82% cases. Gestational age at termination of pregnancy, when compared with different characteristics of fibroid, like type (p value 0.663), location (p value 0.552) and number of fibroid (p value 0.112), did not show any significant association. Similarly, maternal complications also did not show significant association (p value >0.05) with different characters of fibroid. Conclusion: Pregnancies with fibroid are high-risk pregnancies that are linked to difficulties throughout the antepartum, intrapartum, and postpartum periods, as well as increased chances of cesarean delivery and PPH.
子宫肌瘤是女性生殖系统最常见的良性肿瘤，在妊娠期的发生率显著较低。这可能是因为子宫肌瘤与不孕以及体外受精（IVF）后的低着床率有关。本研究的目的是观察一家三级医院中子宫肌瘤患者的产科结局及其影响。
本研究为一项观察性队列研究，评估了合并子宫肌瘤的妊娠病例。研究在印度中部一所医学院的妇产科进行，从2021年11月1日至2022年7月31日，为期9个月。纳入所有产前或孕期经超声（USG）确诊有子宫肌瘤的孕妇。记录所有人口统计学信息、实验室检查和超声检查结果，并评估其分娩方式、产科并发症（如有）及新生儿结局。
根据纳入和排除标准，共纳入110例病例。大多数患者（42.73%）年龄在26至30岁之间。在本研究中，大多数病例足月分娩（80.9%）。最常见的分娩方式是剖宫产（61.82%）。孕期主要并发症为先兆早产（21.82%）和输血（20.00%），而产后出血（PPH）发生率为9.09%，47例患者（42.72%）在整个孕期无症状。本研究中的主要新生儿结局为入住新生儿重症监护病房（NICU）（20%）、需要新生儿复苏（14.55%）以及新生儿死亡率为1.82%。妊娠终止时的孕周与肌瘤的不同特征（如类型，p值0.663；位置，p值0.552；肌瘤数量，p值0.112）相比，未显示出任何显著关联。同样，母亲并发症与肌瘤的不同特征也未显示出显著关联（p值>0.05）。结论：合并子宫肌瘤的妊娠为高危妊娠，与整个产前、产时和产后期间的困难以及剖宫产和产后出血几率增加有关。
