孕早期血液学参数与妊娠期糖尿病风险——中国北京，2017 - 2020年
Hematological Parameters in the First Trimester and the Risk of Gestational Diabetes Mellitus - Beijing, China, 2017-2020.
作者信息
Lyu Xinyi, Jia Jiajing, Yang Haishan, Deng Yuzhi, Wu Hanbin, Wang Shuo, Zhao Chuanyu, Lei Jueming, Zou Xiaoxuan, Yang Ying
机构信息
Graduate School of Peking Union Medical College, Beijing Municipality, China.
National Research Institute for Family Planning, Beijing Municipality, China.
出版信息
China CDC Wkly. 2023 Mar 3;5(9):194-200. doi: 10.46234/ccdcw2023.035.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Hematological parameters may indicate the presence of chronic low-grade inflammation and increasing viscosity, which are involved in the pathological processes of gestational diabetes mellitus (GDM). However, the association between several hematological parameters in early pregnancy and GDM has yet to be elucidated.
WHAT IS ADDED BY THIS REPORT?: Hematological parameters in the first trimester, particularly red blood cell (RBC) count and systematic immune index, have a significant impact on GDM incidence. The neutrophils (NEU) count in the first trimester was particularly pronounced for GDM. The upward trend of RBC, white blood cell (WBC), and NEU counts was consistent across all GDM subtypes.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Early pregnancy hematological parameters are associated with the risk of GDM.
关于该主题已知的信息有哪些？：血液学参数可能表明存在慢性低度炎症和血液黏稠度增加，这与妊娠期糖尿病（GDM）的病理过程有关。然而，孕早期多种血液学参数与GDM之间的关联尚未阐明。
本报告补充了哪些内容？：孕早期的血液学参数，尤其是红细胞（RBC）计数和系统免疫指数，对GDM的发生率有显著影响。孕早期的中性粒细胞（NEU）计数对GDM的影响尤为明显。所有GDM亚型的RBC、白细胞（WBC）和NEU计数均呈上升趋势。
对公共卫生实践有何启示？：孕早期血液学参数与GDM风险相关。
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