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血型和血液学参数与早孕期妊娠期糖尿病无关(机构经验)。

Blood Groups and Hematological Parameters Do Not Associate with First Trimester Gestational Diabetes Mellitus (Institutional Experience).

机构信息

Department of Obstetrics and Gynaecology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia

Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan, Kingdom of Saudi Arabia.

出版信息

Ann Clin Lab Sci. 2021 Jan;51(1):97-101.

Abstract

OBJECTIVE

There are few published researches on blood groups, hematological parameters [hemoglobin, red cell distribution width (RDW), white blood cells (WBCs), mean platelets volume (MPV)] and gestational diabetes mellitus (GDM). The aim of this study was to investigate the association of haematological indices with GDM in early pregnancy.

METHODS

The study was carried out at Saad Abuelela Hospital (Khartoum, Sudan) during March-November of 2018. Pregnant Sudanese women in early pregnancy (gestational age <14 weeks) were enrolled in the study. The details of the medical and obstetrics history were recorded. The women were then followed up until 24-28 weeks of gestation when a 75-gram oral glucose tolerance test was performed.

RESULTS

Two hundred and fifty-three women at 10.2 week of gestational age completed the follow-up. The mean (SD) of the age and gravidity at the initial antenatal visit were 28.03 (5.6) years, 2.32 (2.41). The mean (SD) of body mass index (BMI) was 27.28 (24.41-30.80) kg/m. Fifty women (19.8%) had GDM. Age, parity, BMI, place of residence, employment and education were not significantly different between the two groups. Moreover, there was no significant difference in the blood groups and hematological parameters between women with and without GDM.

CONCLUSION

In this study, the blood groups and other hematological parameters were not different between women with and without GDM.

摘要

目的

关于血型、血液学参数[血红蛋白、红细胞分布宽度(RDW)、白细胞(WBCs)、平均血小板体积(MPV)]和妊娠期糖尿病(GDM)的研究较少。本研究旨在探讨血液学指标与早期妊娠 GDM 的关系。

方法

该研究于 2018 年 3 月至 11 月在苏丹喀土穆的 Saad Abuelela 医院进行。纳入了处于早孕(妊娠龄<14 周)的苏丹孕妇。记录了她们的医疗和产科史详细信息。然后对这些女性进行随访,直到 24-28 周妊娠时进行 75 克口服葡萄糖耐量试验。

结果

253 名 10.2 周妊娠龄的女性完成了随访。初诊时的平均(SD)年龄和孕次分别为 28.03(5.6)岁,2.32(2.41)次。平均(SD)体重指数(BMI)为 27.28(24.41-30.80)kg/m2。50 名女性(19.8%)患有 GDM。两组之间的年龄、产次、BMI、居住地、就业和教育状况无显著差异。此外,GDM 组和非 GDM 组之间的血型和血液学参数也无显著差异。

结论

在本研究中,GDM 组和非 GDM 组之间的血型和其他血液学参数没有差异。

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