Mikhail G R, Boulos R S, Knighton R S, Rogers J S, Malik G, Ditmars D M, Nichols R D
J Dermatol Surg Oncol. 1986 May;12(5):459-64. doi: 10.1111/j.1524-4725.1986.tb01935.x.
The direct spread of basal cell carcinoma (BCC) into the bones of the cranium takes a long period. In its early stages, it may not be detectable by radiography or computerized tomography, but can be visible as pitting during surgery. Invasion through the thickness of the calvarium due to extension of a BCC of the scalp, or involvement of the cribriform plate by spread from an intranasal lesion, is serious. Examples of cranial invasion by BCC are presented. The methods used in diagnosis and treatment are outlined.
基底细胞癌（BCC）直接扩散至颅骨需很长时间。在其早期阶段，通过X线摄影或计算机断层扫描可能无法检测到，但在手术过程中可表现为凹陷。由于头皮BCC扩展导致颅骨全层受侵，或鼻内病变蔓延累及筛板，情况较为严重。本文列举了BCC侵犯颅骨的病例，并概述了诊断和治疗方法。
