Department of Medical Imaging, ONIRIS, Nantes-Atlantic College of Veterinary Medicine, Food Science and Engineering, CS 40706, 44307 NANTES CEDEX 3, France (Kerbrat-Copy, Fusellier); Clinique VetRef, 7 rue James Watt, 49070 Beaucouzé, France (Jossier); INSERM, UMRS 1229, Regenerative Medicine and Skeleton (RMeS), Université de Nantes, ONIRIS, Nantes, F-44042, France (Fusellier).
Can Vet J. 2023 Apr;64(4):344-350.
A 1-year-old, intact female, mixed-breed dog (border collie and springer spaniel) was initially evaluated for lethargy, fever, and ataxia and subsequently evaluated 2.5 y later following the onset of seizures. Over a 3-year interval, the dog underwent 3 computed tomography (CT) and 1 magnetic resonance imaging (MRI) examinations. A voluminous hyperattenuating lesion with a mass effect, exhibiting weak postcontrast enhancement and associated with surrounding diffuse parenchymal hypoattenuation, was observed in the first CT examination (3 d after initial clinical signs). The second CT examination (11 d later) revealed a hypoattenuating lesion with ring postcontrast enhancement. A clear reduction of the size of the mass, which presented as hyperattenuating with a severely postcontrast-enhanced center, was noted in the third CT examination (2.5 y after initial clinical signs and 3 mo after onset of seizures). The MRI examination, performed 3 mo after the third CT examination, showed a small lesion, T2*-gradient echo hypointense, with no peripheral halo noted in T2-weighted fluid-attenuated inversion recovery and with serpentiform enhancement from within the lesion to the meningeal region. These sequential imaging findings were consistent with intracerebral hemorrhage. Key clinical message: To the authors' knowledge, this is the first case of hyperthermia associated with intracerebral hemorrhage in a dog, although this is a common finding in human medicine. An intracerebral hemorrhage should be included in the differential diagnosis of an intracerebral mass, and performing sequential imaging examinations can help clarify the diagnosis.
一只 1 岁、未绝育的雌性混血犬（边牧和英国激飞猎犬混种），最初因嗜睡、发热和共济失调就诊，随后在发病后 2.5 年因癫痫发作再次就诊。在 3 年的时间里，这只狗接受了 3 次计算机断层扫描（CT）和 1 次磁共振成像（MRI）检查。首次 CT 检查（初次临床症状出现后 3 天）显示，存在一个体积较大的高信号病变，伴有占位效应，呈弱对比增强，伴有周围弥漫性实质低信号。第二次 CT 检查（11 天后）显示一个低信号病变，呈环形对比增强。第三次 CT 检查（初次临床症状出现后 2.5 年，癫痫发作后 3 个月）显示，病变体积明显缩小，呈高信号，中心强烈对比增强。第三次 CT 检查后 3 个月进行的 MRI 检查显示，病变呈小 T2*-梯度回波低信号，T2 加权液体衰减反转恢复未见周围晕环，病变内呈蛇形强化至脑膜区。这些连续的影像学表现符合脑出血。关键临床信息：据作者所知，这是首例与脑出血相关的犬类体温升高病例，尽管这在人类医学中很常见。脑出血应纳入颅内占位病变的鉴别诊断，进行连续影像学检查有助于明确诊断。
