Hiller Sonia, Kowalewska Inga, Czerniawska-Piątkowska Ewa, Banaszewska Dorota
Department of Genetics, Szczecin, Poland.
Department of Ruminant Science, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, 70-310 Szczecin, Poland.
J Vet Res. 2023 Mar 28;67(1):123-129. doi: 10.2478/jvetres-2023-0018. eCollection 2023 Mar.
Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products.
The study used amplification-created restriction site and PCR-restriction fragment length polymorphism to analyse single nucleotide polymorphisms of the gene encoding the BMAP-34 protein in cattle, at positions 2,383 > and 2,468 > . The material was collected from 279 Polish Black-and-White Holstein-Friesian dairy cows.
There were statistically significant differences between milk performance parameters in cows with the I and fI genotypes. In the case of the I polymorphism, the highest milk yield and protein and lactose content and the lowest somatic cell count in milk were observed for the genotype, while the fat content was the highest in milk from cows with the GG genotype. In the case of the /fI polymorphism, the highest protein and lactose content in milk was observed for the genotype.
The results were statistically significant, which suggests that the search for relationships can be continued, and that the results can be used to improve selection programmes supporting dairy farming.
抗菌肽，包括cathelicidins，在农场动物中发挥着重要作用，影响动物福利、免疫力，进而影响动物产品质量。
本研究采用扩增产生的限制性位点和PCR-限制性片段长度多态性分析牛BMAP-34蛋白编码基因在2383和2468位点的单核苷酸多态性。材料取自279头波兰黑白花荷斯坦-弗里生奶牛。
I型和fI型基因型奶牛的产奶性能参数存在统计学显著差异。就I多态性而言，基因型奶牛的产奶量、蛋白质和乳糖含量最高，牛奶中的体细胞计数最低，而GG基因型奶牛的牛奶脂肪含量最高。就/fI多态性而言，基因型奶牛的牛奶蛋白质和乳糖含量最高。
结果具有统计学意义，这表明可以继续寻找相关性，且这些结果可用于改进支持奶牛养殖的选择方案。
