Rowe M S, Bailey J, Ownby D R
J Allergy Clin Immunol. 1986 May;77(5):714-9. doi: 10.1016/0091-6749(86)90416-1.
A number of individuals with perennial or seasonal rhinoconjunctivitis state that their symptoms may suddenly worsen on exposure to lawn mowing. Many allergists have believed that this was related to the agitation of molds deposited on the grass. We studied 50 consecutive new patients with rhinitis using history, skin testing, total and specific IgE assays, and nasal smears. Twenty-five patients gave histories of minimal or no change in their nasal symptoms with exposure to lawn mowing, whereas 11 patients had definite, but mild, symptoms, and 14 patients had severe symptoms. Positive skin tests to grasses, trees, and weed pollens were more frequent in those patients with symptoms exacerbated by lawn mowing (p less than 0.03). Symptomatic patients also had higher serum concentrations of total IgE (p less than 0.008) and grass-pollen specific IgE (p = 0.0004). The frequencies of positive skin tests to ragweed pollens, house dust, molds, and grass leaves, as well as the percentage of nasal eosinophils, were not different in the symptomatic and asymptomatic groups. No significant association was found between symptoms and IgE antibodies to molds or grass-leaf extract. We believe that the increased nasal and ocular symptoms coincident with lawn mowing are allergic phenomena significantly associated with skin test sensitivity and specific IgE antibodies to grass pollens but not with sensitivity or specific IgE to molds or grass-leaf extract.
许多患有常年性或季节性鼻结膜炎的人表示，他们的症状在接触割草后可能会突然加重。许多过敏症专科医生认为，这与沉积在草上的霉菌被搅动有关。我们使用病史、皮肤试验、总IgE和特异性IgE检测以及鼻涂片，对50例连续性鼻炎新患者进行了研究。25例患者表示接触割草后鼻部症状轻微变化或无变化，而11例患者有明确但轻微的症状，14例患者有严重症状。在割草后症状加重的患者中，对草、树和杂草花粉的皮肤试验阳性更为频繁（p<0.03）。有症状的患者血清总IgE浓度也更高（p<0.008），草花粉特异性IgE浓度也更高（p=0.0004）。有症状组和无症状组对豚草花粉、屋尘、霉菌和草叶的皮肤试验阳性频率以及鼻嗜酸性粒细胞百分比没有差异。在症状与针对霉菌或草叶提取物的IgE抗体之间未发现显著关联。我们认为，与割草同时出现的鼻部和眼部症状加重是过敏现象，与皮肤试验敏感性以及针对草花粉的特异性IgE抗体显著相关，但与针对霉菌或草叶提取物的敏感性或特异性IgE无关。
