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功能性神经障碍,这类疾病应由神经科医生进行管理,还是说神经科医生正在一个资源不足的危险领域徘徊?

Functional Neurologic Disorders, disorders to be managed by neurologists, or are neurologists wandering in a dangerous field with inadequate resources?

作者信息

Onofrj Marco, Ajdinaj Paola, Digiovanni Anna, Malek Naveed, Martinotti Giovanni, Ferro Filippo Maria, Russo Mirella, Thomas Astrid, Sensi Stefano Luca

机构信息

Department of Neuroscience, Imaging, and Clinical Sciences, "G. D'Annunzio University" of Chieti-Pescara, Chieti, Italy.

Center for Advanced Studies and Technology (CAST), "G. D'Annunzio University" of Chieti-Pescara, Chieti, Italy.

出版信息

Front Psychiatry. 2023 Mar 17;14:1120981. doi: 10.3389/fpsyt.2023.1120981. eCollection 2023.

DOI:10.3389/fpsyt.2023.1120981
PMID:37009111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10064068/
Abstract

In recent years, some neurologists reconsidered their approach to Medically Unexplained Symptoms and proposed Functional Neurologic Disorders (FND) as a new entity, claiming that neurology could offer alternative treatment options to the psychotherapies provided in psychiatry settings. FNDs, for this purpose, should include only the disorders listed as Conversion from the Somatic Symptom and Related Disorders (SSRD) group. The present review analyzes the rationale of this position and challenges the arguments provided for its support. The review also discusses the systematization of these disorders as provided by public health systems. It outlines risks stemming from economic support and public funding uncertainty, given their negligible epidemiological dimensions resulting from the parcellation of SSRD. The review underlines the unresolved issue of Factitious Disorders, which are in the same SSRD category of the international classification but are, nonetheless, overlooked by the theoretical proponents of the FND entity. Comorbidity with other psychiatric disorders is also analyzed. We propose a model that supports the continuum between different SSRD conditions, including Factitious Disorders. The model is based on the emergence of feigned death reflex and deception from frontal lobe dysfunction. Finally, the paper summarizes the wealth of historical psychiatric and psychodynamic approaches and critical reviews. The study also puts in context the categorization and interpretation efforts provided by the most eminent researchers of the past century.

摘要

近年来,一些神经科医生重新审视了他们对医学上无法解释的症状的处理方法,并提出功能性神经障碍(FND)作为一个新的实体,声称神经科可以提供替代精神病学环境中所提供心理治疗的治疗选择。为此,FND应仅包括躯体症状及相关障碍(SSRD)组中列为转换障碍的那些疾病。本综述分析了这一立场的基本原理,并对支持该立场的论据提出质疑。综述还讨论了公共卫生系统对这些疾病的系统化分类。鉴于SSRD分类导致这些疾病的流行病学规模可忽略不计,综述概述了经济支持和公共资金不确定性带来的风险。综述强调了诈病障碍这一未解决的问题,诈病障碍与国际分类中SSRD属于同一类别,但却被FND实体的理论支持者所忽视。还分析了与其他精神障碍的共病情况。我们提出了一个支持不同SSRD状况(包括诈病障碍)之间连续性的模型。该模型基于额叶功能障碍导致的假死反射和欺骗行为的出现。最后,本文总结了丰富的历史精神病学和心理动力学方法及批判性评论。该研究还结合了过去一个世纪最杰出研究人员所做的分类和解释工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/1a5b4a97d31b/fpsyt-14-1120981-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/31f2470cc511/fpsyt-14-1120981-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/a06afd1af9c7/fpsyt-14-1120981-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/ea79da30bc4f/fpsyt-14-1120981-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/1a5b4a97d31b/fpsyt-14-1120981-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/31f2470cc511/fpsyt-14-1120981-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/a06afd1af9c7/fpsyt-14-1120981-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/ea79da30bc4f/fpsyt-14-1120981-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5009/10064068/1a5b4a97d31b/fpsyt-14-1120981-g004.jpg

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本文引用的文献

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The natural history of terms describing functional (neurological) disorders in the medical literature of the last 60 years.过去60年医学文献中描述功能性(神经)障碍术语的自然史。
J Neurol. 2023 Apr;270(4):2010-2017. doi: 10.1007/s00415-022-11526-9. Epub 2022 Dec 22.
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Altered Medial Prefrontal Connectivity in Parkinson's Disease Patients with Somatic Symptoms.帕金森病伴躯体症状患者内侧前额叶连接改变。
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