Sassalos Thérèse M, Patel Nish, Andrews Chris, Smith Stephen J, Musch David C, Besirli Cagri G
Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
J Vitreoretin Dis. 2020 Jan 23;4(4):306-311. doi: 10.1177/2474126419899514. eCollection 2020 Jul-Aug.
Intravitreal injection therapy (IVT) is the most performed procedure in ophthalmology. This study was conducted to determine current trends in IVT delivery.
An online, 31-question, multiple-choice survey was sent to 1677 retina specialists. The survey consisted of 3 sections: general questions, procedure technique, and postprocedure technique.
A total of 264 (16%) retina specialists completed the survey. The use of povidone-iodine (100%) and small-gauge needles (97%) was common, whereas ocular anesthesia was split among lidocaine gel (31%), lidocaine drops (25%), subconjunctival lidocaine (28%), and lidocaine-soaked pledgets (15%). More than 85% indicated povidone-iodine contributes to post-IVT corneal toxicity, and 12% reported that a needlestick injury to physician or staff occurred during IVT.
Key areas for IVT improvement include optimized ocular anesthesia, development of a guarded needle for ocular drug delivery, and formulation of a less toxic ocular antiseptic.
玻璃体内注射疗法（IVT）是眼科最常施行的手术。本研究旨在确定IVT给药的当前趋势。
向1677名视网膜专家发送了一份包含31个问题的在线多项选择题调查问卷。该调查问卷包括3个部分：一般问题、手术技术和术后技术。
共有264名（16%）视网膜专家完成了调查。聚维酮碘（100%）和小口径针头（97%）的使用很常见，而眼部麻醉在利多卡因凝胶（31%）、利多卡因滴眼液（25%）、结膜下利多卡因（28%）和利多卡因浸泡棉球（15%）之间分布。超过85%的人表示聚维酮碘会导致IVT术后角膜毒性，12%的人报告在IVT期间医生或工作人员发生了针刺伤。
IVT改进的关键领域包括优化眼部麻醉、开发用于眼部药物递送的防护针头以及配制毒性较小的眼部防腐剂。
