Graney A S, Smith L B, Hammer K A
J Am Diet Assoc. 1986 May;86(5):630-5.
The study of 325 patients who underwent gastric partitioning (stapling) was undertaken to assess the complications and weight-loss records over a 5-year period. A subgroup of 15 patients was studied to determine protein status preoperatively and 2, 4, and 6 months after surgery. Laboratory tests, anthropometric measures, and food records were used to assess patient health and nutritional status. Four operative techniques have been used by a surgeon in Reno, NV, since 1979. The main postoperative complication in the first two procedures, a nonreinforced horizontal staple line (Groups 1 and 2), was staple line disruption and, therefore, poor weight-loss results. The staple line was reinforced in the next 193 patients (Group 3), and the patients followed a blenderized diet for 8 weeks postoperatively. Persistent vomiting was the most common problem in that group; 24% required dilatation of the stoma via gastroscopy. The vertical staple procedure was adopted for the next 48 patients (Group 4) to further minimize disruption and severe vomiting. Other operative complications were relatively few. At 48 and 18 months, respectively, Groups 3 and 4 showed an average weight loss of 27% of the preoperative weight. Eating patterns and food tolerances changed dramatically postoperatively, and protein intake dropped significantly. Mean protein intakes below standard recommended dietary allowance (RDA) were observed in a subgroup of Groups 3 and 4. However, the mean total lymphocyte count and albumin values demonstrated that patients were not compromising visceral proteins. The mean creatinine height indexes and arm muscle areas showed no significant difference in somatic protein status.(ABSTRACT TRUNCATED AT 250 WORDS)
对325例行胃分隔术(吻合器手术)的患者进行了研究,以评估其5年期间的并发症及体重减轻记录。对15例患者的亚组进行研究,以确定术前以及术后2个月、4个月和6个月时的蛋白质状况。采用实验室检测、人体测量指标及饮食记录来评估患者的健康和营养状况。自1979年以来,内华达州里诺市的一名外科医生使用了四种手术技术。在前两种手术(第1组和第2组)中,主要的术后并发症是未加固的水平吻合线,出现了吻合线破裂,因此体重减轻效果不佳。接下来的193例患者(第3组)的吻合线进行了加固,这些患者术后8周采用流食饮食。持续性呕吐是该组最常见的问题;24%的患者需要通过胃镜进行造口扩张。接下来的48例患者(第4组)采用了垂直吻合术,以进一步减少破裂和严重呕吐的发生。其他手术并发症相对较少。第3组和第4组分别在术后48个月和18个月时,平均体重减轻了术前体重的27%。术后饮食模式和食物耐受性发生了显著变化,蛋白质摄入量大幅下降。在第3组和第4组的一个亚组中,观察到平均蛋白质摄入量低于标准推荐膳食摄入量(RDA)。然而,平均总淋巴细胞计数和白蛋白值表明患者并未损害内脏蛋白。平均肌酐身高指数和上臂肌肉面积在身体蛋白质状况方面无显著差异。(摘要截短至250字)