Pace W G, Martin E W, Tetirick T, Fabri P J, Carey L C
Ann Surg. 1979 Sep;190(3):392-400. doi: 10.1097/00000658-197909000-00015.
The complication rate in jejunoileal bypass for morbid obesity is unacceptably high. Gastric bypass is technically difficult. In our series, 115 patients have undergone gastric partitioning for morbid obesity. The operation consists of stapling across the stomach below the gastroesophageal junction, leaving a gastric food reservoir of 50--60 cc. A 1 cm opening is left in the central portion of the staple line, allowing slow emptying into the distal stomach. The result is a reduced eating capacity and frequency which produce loss in weight. Three-quarters of the patients are women, and the age range is 17--62 years. Preoperative weights averaged 147 kg. Mean operative time was 48 minutes, and postoperative stay was 6.2 days. All patients were extensively evaluated preoperatively with upper GI series, cholecystogram, a number of blood chemistry tests, and endocrinologic and psychiatric consultations. All patients underwent a preoperative Minnesota Multiphasic Personality Inventory test. Cholecystectomy for cholelithiasis was performed on 18% of the patients at the time of operation. Of the seven patients operated on more than one year ago, five have lost an average of 31.6% of their preoperative weight. Of the 12 operated on less than one year but more than six months ago, eight have lost an average of 21% of their initial weight. The early failure rate of 33% has been reduced to 15% at present. One death occurred from pulmonary embolus 10 days following discharge, giving a mortality rate of .08%. The complication rate is 10%, comprising two pulmonary emboli, two psychoses, one wound dehiscence, one wound hernia, and ten wound infections, six of which were minor. There have been no complications of ulcer disease, reflux esophagitis, liver disease, renal disease, or metabolic disorders. Gastric partitioning is a safe, fast effective alternative for the surgical treatment of morbid obesity.
空回肠分流术治疗病态肥胖的并发症发生率高得令人难以接受。胃分流术在技术上难度较大。在我们的病例系列中,115例患者接受了胃分隔术治疗病态肥胖。手术包括在胃食管交界处下方横跨胃进行吻合器缝合,留下一个50至60立方厘米的胃食物储存袋。在吻合线的中央部分留一个1厘米的开口,使食物缓慢排入远端胃。结果是进食量和进食频率减少,从而导致体重减轻。四分之三的患者为女性,年龄范围为17至62岁。术前平均体重为147千克。平均手术时间为48分钟,术后住院时间为6.2天。所有患者术前均接受了全面评估,包括上消化道造影、胆囊造影、多项血液化学检查以及内分泌和精神科会诊。所有患者均进行了术前明尼苏达多相人格量表测试。18%的患者在手术时因胆结石接受了胆囊切除术。在一年多前接受手术的7例患者中,5例平均减轻了术前体重的31.6%。在不到一年但超过六个月前接受手术的12例患者中,8例平均减轻了初始体重的21%。早期失败率已从33%降至目前的15%。1例患者出院后10天因肺栓塞死亡,死亡率为0.08%。并发症发生率为10%,包括2例肺栓塞、2例精神病、1例伤口裂开、1例伤口疝和10例伤口感染,其中6例为轻微感染。未出现溃疡病、反流性食管炎、肝病、肾病或代谢紊乱等并发症。胃分隔术是治疗病态肥胖的一种安全、快速有效的手术替代方法。