2021年，日本埼玉县儿童呼吸道合胞病毒（RSV）感染出现非典型激增。
An atypical surge in RSV infections among children in Saitama, Japan in 2021.
作者信息
Ohnishi Takuma, Kang Yumi, Kawano Yutaka, Kunikata Tetsuya, Ichihashi Ko
机构信息
Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Division of Infectious Diseases, Immunology and Allergy, Saitama Children's Medical Center, 1-2 Shintoshin, Chuou-ku, Saitama-shi, Saitama 330-8777, Japan.
出版信息
IJID Reg. 2022 Dec 21;7:124-126. doi: 10.1016/j.ijregi.2022.12.006. eCollection 2023 Jun.
BACKGROUND
In 2021, atypical seasonal respiratory syncytial virus (RSV) outbreaks were observed in several countries. However, the peak, duration, and severity of these outbreaks have not been assessed.
METHODS
Data were collected from almost all facilities with pediatric wards in Saitama Prefecture, Japan. Variables included the weekly number of patients admitted with RSV infection, their age, and the number of patients who required intubation. The average weekly admission rates (number of patients admitted divided by the number of hospitals) were compared by pre-pandemic year (2018 and 2019) and 2021, using analysis of variance.
RESULTS
In 2021, 1354 patients were admitted with RSV infection. The median age of the patients was < 12 months. The admission rate peaked around week 30. The slope of the peak in 2021 was markedly steeper than in the previous years. The mean weekly admission rate did not differ significantly between 2018, 2019, and 2021 ( = 0.77). The proportions of intubated patients did not differ significantly over the 4 years (2018-2021, = 0.68).
CONCLUSION
The overall number of RSV admissions and intubation rate in 2021 were similar to those in pre-pandemic years.
背景
2021年，在多个国家观察到非典型季节性呼吸道合胞病毒（RSV）爆发。然而，这些疫情的高峰期、持续时间和严重程度尚未得到评估。
方法
收集了日本埼玉县几乎所有设有儿科病房的医疗机构的数据。变量包括每周因RSV感染入院的患者数量、年龄以及需要插管的患者数量。使用方差分析比较了疫情前年份（2018年和2019年）与2021年的平均每周入院率（入院患者数量除以医院数量）。
结果
2021年，有1354例患者因RSV感染入院。患者的中位年龄小于12个月。入院率在第30周左右达到峰值。2021年峰值的斜率明显比前几年更陡。2018年、2019年和2021年的平均每周入院率差异无统计学意义（F = 0.77）。4年（2018 - 2021年）间插管患者的比例差异无统计学意义（F = 0.68）。
结论
2021年RSV入院的总数和插管率与疫情前年份相似。
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