Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Cytopathology. 2023 Jul;34(4):388-394. doi: 10.1111/cyt.13230. Epub 2023 Apr 3.
The cytomorphological features of benign mesenchymal tumours of the tongue have rarely been reported. Herein, we present the cytomorphological features of adult-type rhabdomyoma, which occurred in the tongue of a female patient, and granular cell tumour (GCT), which occurred in the tongue of a male patient; both patients were in their mid-50s. The cytological features of the adult-type rhabdomyoma case included large polygonal to ovoid cells with abundant and granular cytoplasm with predominantly peripherally located, uniform, round to oval nuclei and small nucleoli. Cross-striation and crystalline intracytoplasmic structures were not seen. The cytological features of the GCT case included large cells with abundant granular pale cytoplasm, small round nuclei and small distinct nucleoli. The cytological differential diagnoses of these tumours overlap; thus, the cytological findings of the different entities included in their differential diagnoses are discussed.
良性舌部间叶性肿瘤的细胞学特征鲜有报道。本文报道了 2 例 50 多岁舌部成人型横纹肌瘤和颗粒细胞瘤的细胞学特征，男性患者舌部发生颗粒细胞瘤，女性患者舌部发生成人型横纹肌瘤。成人型横纹肌瘤的细胞学特征包括大的多边形至卵圆形细胞，胞质丰富且颗粒状，核偏位，呈均匀的圆形或椭圆形，核仁小。未见横纹和细胞内结晶结构。颗粒细胞瘤的细胞学特征包括大的细胞，胞质丰富、颗粒状、淡染，细胞核小而圆，核仁小而明显。这些肿瘤的细胞学鉴别诊断存在重叠；因此，讨论了其鉴别诊断中不同实体的细胞学表现。
