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[子宫内膜异位症内外异症的综合组织发生学概念]

[An integrated histogenetic concept of internal and external endometriosis].

作者信息

Minh H N, Smadja A, Orcel L

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1986;15(1):29-35.

PMID:3700997
Abstract

The authors have studied the embryology of the uterus and have studied the comparative morphology of the internal foci of endometriosis, as well as the endometrium itself during the menstrual cycle. These studies have led them to think that the foci of endometriosis, whether they are internal or external, come from cells of coelomic mesothelium that persists in the transitional zone between the myometrium and the endometrium of the uterus, or in the mesothelium that covers the ovary, the tube and the pelvis under the stimulus of substances that are present in degenerate endometrial tissues during menstruation. This unitary idea of histogenesis makes it possible to consider under one heading, if not to unite, all endometriosis occurring anywhere according to their histogenic presentation under the same conditions of the tissues that surround them. It also makes it possible to explain the morphological similarity of endometriosis with the endometrium, although the biological behaviour of the two tissues is different. There is therefore a relationship between endometrium and endometriosis but not a filial one.

摘要

作者们研究了子宫的胚胎学,并研究了子宫内膜异位症内部病灶的比较形态学,以及月经周期中子宫内膜本身的形态学。这些研究使他们认为,子宫内膜异位症的病灶,无论其是内部的还是外部的,都来自于体腔间皮细胞,这些细胞在子宫肌层和子宫内膜之间的过渡区持续存在,或者在月经期间退化的子宫内膜组织中存在的物质刺激下,存在于覆盖卵巢、输卵管和盆腔的间皮中。这种组织发生的统一观点使得有可能在一个标题下考虑,如果不能将其统一的话,所有根据其组织发生表现,在相同周围组织条件下发生在任何部位的子宫内膜异位症。这也使得有可能解释子宫内膜异位症与子宫内膜的形态相似性,尽管这两种组织的生物学行为不同。因此,子宫内膜与子宫内膜异位症之间存在一种关系,但不是亲子关系。

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