Trimboli Michele, Marsico Oreste, Troisi Letizia, Fasano Francesco
Department of Neurology, AOR San Carlo, Potenza, Italy.
Department of Medical & Surgical Sciences, Institute of Neurology, Magna Græcia University, Catanzaro, Italy.
Pain Manag. 2023 Mar;13(3):185-192. doi: 10.2217/pmt-2022-0082. Epub 2023 Apr 3.
To assess the safety and efficacy of external trigeminal neurostimulation (e-TNS) as an add-on treatment in chronic migraine (CM) prophylaxis. A prospective observational open-label study was conducted on CM patients observed at baseline and 3 months after starting daily sessions of 20 min with e-TNS (Cefaly). A total of 24 volunteers affected by CM according to the ICHD-3 were included. At the 3 month follow-up, a >30% reduction of headache days was observed in four (16.5%) of 24 patients; a marginal headache improvement was observed in ten (42%) patients, with no or minor adverse effects (four of 24 patients). e-TNS may constitute a safe preventive treatment in CM, its limited efficacy is not statistically significant.
评估外部三叉神经神经刺激（e-TNS）作为慢性偏头痛（CM）预防附加治疗的安全性和有效性。对符合国际头痛疾病分类第三版（ICHD-3）标准的CM患者进行了一项前瞻性观察性开放标签研究，在基线时以及开始每天20分钟使用e-TNS（Cefaly）治疗3个月后对患者进行观察。根据ICHD-3，共纳入了24名CM志愿者。在3个月的随访中，24名患者中有4名（16.5%）头痛天数减少超过30%；10名（42%）患者头痛有轻微改善，且无或仅有轻微不良反应（24名患者中的4名）。e-TNS可能是CM的一种安全预防治疗方法，但其有限的疗效无统计学意义。
